Castle Biosciences, Inc.

NasdaqGM:CSTL Stock Report

Market Cap: US$748.9m

Castle Biosciences Valuation

Is CSTL undervalued compared to its fair value, analyst forecasts and its price relative to the market?

Valuation Score

4/6

Valuation Score 4/6

  • Below Future Cash Flow Value

  • Significantly Below Future Cash Flow Value

  • Price-To-Sales vs Peers

  • Price-To-Sales vs Industry

  • Price-To-Sales vs Fair Ratio

  • Analyst Forecast

Share Price vs Future Cash Flow Value

What is the Fair Price of CSTL when looking at its future cash flows? For this estimate we use a Discounted Cash Flow model.

Ultimate guide to DCF valuation for stock investing

Learn how to determine fair value like the best investors in the world.

Below Future Cash Flow Value: CSTL ($23.43) is trading below our estimate of future cash flow value ($90.44)

Significantly Below Future Cash Flow Value: CSTL is trading below future cash flow value by more than 20%.

Key Valuation Metric

Which metric is best to use when looking at relative valuation for CSTL?

Key metric: As CSTL is unprofitable we use its Price-To-Sales Ratio for relative valuation analysis.

The above table shows the Price to Sales ratio for CSTL. This is calculated by dividing CSTL's market cap by their current revenue.
What is CSTL's PS Ratio?
PS Ratio2x
SalesUS$344.23m
Market CapUS$748.93m

Price to Sales Ratio vs Peers

How does CSTL's PS Ratio compare to its peers?

The above table shows the PS ratio for CSTL vs its peers. Here we also display the market cap and forecasted growth for additional consideration.
CompanyForward PSEstimated GrowthMarket Cap
Peer Average2x
OMDA Omada Health
2.7x18.03%US$738.3m
TALK Talkspace
3.8x17.01%US$862.1m
PNTG Pennant Group
1.2x10.69%US$1.1b
ASTH Astrana Health
0.4x10.75%US$1.4b
CSTL Castle Biosciences
2x8.00%US$748.9m

Price-To-Sales vs Peers: CSTL is expensive based on its Price-To-Sales Ratio (2x) compared to the peer average (2x).

Historical Price to Sales Ratio

Historical Price to Sales Ratio compares a stock's price to its sales over time. Higher ratios indicate that investors are willing to pay more for the stock.

Fetching historical data

Price to Sales Ratio vs Industry

How does CSTL's PS Ratio compare vs other companies in the US Healthcare Industry?

27 CompaniesPrice / SalesEstimated GrowthMarket Cap
COR Cencora
0.2x6.60%US$63.21b
CAH Cardinal Health
0.2x8.30%US$50.62b
HUM Humana
0.2x9.26%US$23.82b
CNC Centene
0.1x3.65%US$18.33b
CSTL 2.0xIndustry Avg. 1.2xNo. of Companies27PS012345+
27 CompaniesEstimated GrowthMarket Cap
No more companies

Price-To-Sales vs Industry: CSTL is expensive based on its Price-To-Sales Ratio (2x) compared to the US Healthcare industry average (1.2x).

Price to Sales Ratio vs Fair Ratio

What is CSTL's PS Ratio compared to its Fair PS Ratio? This is the expected PS Ratio taking into account the company's forecast earnings growth, profit margins and other risk factors.

CSTL PS Ratio vs Fair Ratio.
Fair Ratio
Current PS Ratio2x
Fair PS Ratio2.8x

Price-To-Sales vs Fair Ratio: CSTL is good value based on its Price-To-Sales Ratio (2x) compared to the estimated Fair Price-To-Sales Ratio (2.8x).

Analyst Price Targets

What is the analyst 12-month forecast and do we have any statistical confidence in the consensus price target?

The above table shows the analyst CSTL forecast and predictions for the stock price in 12 month’s time.
DateShare PriceAverage 1Y Price TargetDispersionHighLow1Y Actual priceAnalysts
CurrentUS$23.43
US$48.50
+107.00%
5.46%US$52.00US$44.00n/a8
Apr ’27US$25.05
US$48.50
+93.61%
5.46%US$52.00US$44.00n/a8
Mar ’27US$29.57
US$48.50
+64.02%
5.46%US$52.00US$44.00n/a8
Feb ’27US$39.39
US$48.57
+23.31%
6.95%US$52.00US$41.00n/a7
Jan ’27US$38.90
US$40.38
+3.79%
16.19%US$50.00US$30.00n/a8
Dec ’26US$39.12
US$37.25
-4.78%
9.28%US$41.00US$30.00n/a8
Nov ’26US$25.50
US$35.63
+39.71%
9.30%US$41.00US$30.00n/a8
Oct ’26US$23.02
US$35.63
+54.76%
9.30%US$41.00US$30.00n/a8
Sep ’26US$24.01
US$35.63
+48.38%
9.30%US$41.00US$30.00n/a8
Aug ’26US$14.65
US$35.89
+144.98%
9.14%US$41.00US$30.00n/a9
Jul ’26US$20.34
US$35.89
+76.44%
9.14%US$41.00US$30.00n/a9
Jun ’26US$15.97
US$35.89
+124.73%
9.14%US$41.00US$30.00n/a9
May ’26US$19.31
US$38.33
+98.52%
10.51%US$44.00US$30.00n/a9
Apr ’26US$19.78
US$38.89
+96.61%
9.96%US$44.00US$30.00US$25.059
Mar ’26US$21.68
US$39.50
+82.20%
6.45%US$44.00US$36.00US$29.578
Feb ’26US$28.27
US$40.67
+43.85%
10.30%US$50.00US$36.00US$39.399
Jan ’26US$26.65
US$41.56
+55.93%
9.83%US$50.00US$36.00US$38.909
Dec ’25US$30.28
US$41.56
+37.24%
9.83%US$50.00US$36.00US$39.129
Nov ’25US$33.15
US$37.33
+12.62%
13.48%US$45.00US$28.00US$25.509
Oct ’25US$28.09
US$35.56
+26.58%
12.16%US$45.00US$28.00US$23.029
Sep ’25US$29.67
US$35.56
+19.84%
12.16%US$45.00US$28.00US$24.019
Aug ’25US$23.04
US$34.33
+49.02%
9.61%US$40.00US$28.00US$14.659
Jul ’25US$21.19
US$34.33
+62.03%
9.61%US$40.00US$28.00US$20.349
Jun ’25US$23.26
US$34.33
+47.61%
9.61%US$40.00US$28.00US$15.979
May ’25US$22.02
US$33.11
+50.37%
9.17%US$37.00US$28.00US$19.319
Apr ’25US$22.25
US$33.11
+48.81%
9.17%US$37.00US$28.00US$19.789
US$48.5
Fair Value
51.7% undervalued intrinsic discount
8
Number of Analysts

Analyst Forecast: Target price is more than 20% higher than the current share price and analysts are within a statistically confident range of agreement.

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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/04/09 12:58
End of Day Share Price 2026/04/09 00:00
Earnings2025/12/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Castle Biosciences, Inc. is covered by 9 analysts. 8 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Catherine Ramsey SchulteBaird
Mark MassaroBTIG
Kyle MiksonCanaccord Genuity