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Nuvalent, Inc.NasdaqGS:NUVL Stock Report

Market Cap US$5.6b
Share Price
US$81.39
My Fair Value
US$116.38
30.1% undervalued intrinsic discount
1Y-17.9%
7D6.2%
Portfolio Value
View

Nuvalent, Inc.

NasdaqGS:NUVL Stock Report

Market Cap: US$5.6b

Nuvalent (NUVL) Stock Overview

A clinical-stage biopharmaceutical company, engages in the development of therapies for patients with cancer. More details

NUVL fundamental analysis
Snowflake Score
Valuation3/6
Future Growth2/6
Past Performance0/6
Financial Health5/6
Dividends0/6

NUVL Community Fair Values

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Nuvalent, Inc. Competitors

Price History & Performance

Summary of share price highs, lows and changes for Nuvalent
Historical stock prices
Current Share PriceUS$81.39
52 Week HighUS$106.32
52 Week LowUS$55.54
Beta1.29
1 Month Change6.91%
3 Month Change2.15%
1 Year Change-17.87%
3 Year Change318.67%
5 Year Changen/a
Change since IPO334.08%

Recent News & Updates

Recent updates

We're Hopeful That Nuvalent (NASDAQ:NUVL) Will Use Its Cash Wisely

Jun 16
We're Hopeful That Nuvalent (NASDAQ:NUVL) Will Use Its Cash Wisely

Here's Why We're Not Too Worried About Nuvalent's (NASDAQ:NUVL) Cash Burn Situation

Mar 03
Here's Why We're Not Too Worried About Nuvalent's (NASDAQ:NUVL) Cash Burn Situation

Nuvalent: A First Look

Jan 22

Nuvalent: A Logical Acquisition Target

Jan 10

Nuvalent: Steps Toward That Favorable Entry Point

Dec 07

We're Hopeful That Nuvalent (NASDAQ:NUVL) Will Use Its Cash Wisely

Nov 18
We're Hopeful That Nuvalent (NASDAQ:NUVL) Will Use Its Cash Wisely

Nuvalent: Promising Data Keeps Validating Pipeline And Platform

Sep 23

Nuvalent: Likely Approvals Coming Up Do Not Justify This Valuation

Sep 17

Nuvalent: Making Precise Progress In Its Oncology Pipeline

Jun 24

Nuvalent: NVL-655 Could Bring Blockbuster Potential

Jun 14

Nuvalent: Pivotal NSCLC Programs Progressing With Additional Data In 2024

Feb 26

Shareholder Returns

NUVLUS BiotechsUS Market
7D6.2%-2.2%-0.8%
1Y-17.9%-6.8%16.2%

Return vs Industry: NUVL underperformed the US Biotechs industry which returned -6.8% over the past year.

Return vs Market: NUVL underperformed the US Market which returned 16.2% over the past year.

Price Volatility

Is NUVL's price volatile compared to industry and market?
NUVL volatility
NUVL Average Weekly Movement5.2%
Biotechs Industry Average Movement10.3%
Market Average Movement6.5%
10% most volatile stocks in US Market17.1%
10% least volatile stocks in US Market3.0%

Stable Share Price: NUVL has not had significant price volatility in the past 3 months compared to the US market.

Volatility Over Time: NUVL's weekly volatility (5%) has been stable over the past year.

About the Company

FoundedEmployeesCEOWebsite
2017200Jim Porterwww.nuvalent.com

Nuvalent, Inc., a clinical-stage biopharmaceutical company, engages in the development of therapies for patients with cancer. Its lead product candidates are NVL-520, a novel ROS1-selective inhibitor to address the clinical challenges of emergent treatment resistance, central nervous system (CNS)-related adverse events, and brain metastases that may limit the use of ROS1 tyrosine kinase inhibitors (TKIs) for patients with ROS proto-oncogene 1 (ROS1)-positive non-small cell lung cancer (NSCLC) which is under the Phase 2 portion of the ARROS-1 Phase 1/2 clinical trial; NVL-655, a brain-penetrant ALK-selective inhibitor, to address the clinical challenges of emergent treatment resistance, CNS-related adverse events, and brain metastases that might limit the use of first-, second-, and third-generation ALK inhibitors that is under the Phase 2 portion of the ALKOVE-1 clinical trial; and NVL-330, a brain-penetrant human epidermal growth factor receptor 2 (HER2)-selective inhibitor designed to treat tumors driven by HER2ex20, brain metastases, and avoiding treatment-limiting adverse events including due to off-target inhibition of wild-type EGFR that is in Phase 1a/1b clinical trial. The company was incorporated in 2017 and is headquartered in Cambridge, Massachusetts.

Nuvalent, Inc. Fundamentals Summary

How do Nuvalent's earnings and revenue compare to its market cap?
NUVL fundamental statistics
Market capUS$5.59b
Earnings (TTM)-US$343.34m
Revenue (TTM)n/a
0.0x
P/S Ratio
-17.1x
P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
NUVL income statement (TTM)
RevenueUS$0
Cost of RevenueUS$0
Gross ProfitUS$0
Other ExpensesUS$343.34m
Earnings-US$343.34m

Last Reported Earnings

Jun 30, 2025

Next Earnings Date

n/a

Earnings per share (EPS)-4.76
Gross Margin0.00%
Net Profit Margin0.00%
Debt/Equity Ratio0%

How did NUVL perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2025/09/26 21:55
End of Day Share Price 2025/09/26 00:00
Earnings2025/06/30
Annual Earnings2024/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Nuvalent, Inc. is covered by 20 analysts. 13 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Colleen KusyBaird
Peter LawsonBarclays
Richard J. LawGoldman Sachs