Taysha Gene Therapies, Inc.

NasdaqGS:TSHA Stock Report

Market Cap: US$2.1b

Taysha Gene Therapies Valuation

Is TSHA undervalued compared to its fair value, analyst forecasts and its price relative to the market?

Valuation Score

3/6

Valuation Score 3/6

  • Below Future Cash Flow Value

  • Significantly Below Future Cash Flow Value

  • Price-To-Book vs Peers

  • Price-To-Book vs Industry

  • Price-To-Book vs Fair Ratio

  • Analyst Forecast

Share Price vs Future Cash Flow Value

What is the Fair Price of TSHA when looking at its future cash flows? For this estimate we use a Discounted Cash Flow model.

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Below Future Cash Flow Value: TSHA ($6.34) is trading below our estimate of future cash flow value ($59.62)

Significantly Below Future Cash Flow Value: TSHA is trading below future cash flow value by more than 20%.

Key Valuation Metric

Which metric is best to use when looking at relative valuation for TSHA?

Key metric: As TSHA barely has revenue we use its Price-To-Book Ratio for relative valuation analysis.

The above table shows the Price to Book ratio for TSHA. This is calculated by dividing TSHA's market cap by their current book value.
What is TSHA's PB Ratio?
PB Ratio9.6x
BookUS$211.94m
Market CapUS$2.10b

Price to Book Ratio vs Peers

How does TSHA's PB Ratio compare to its peers?

The above table shows the PB ratio for TSHA vs its peers. Here we also display the market cap and forecasted growth for additional consideration.
CompanyForward PBEstimated GrowthMarket Cap
Peer Average29.1x
PGEN Precigen
93.7x65.85%US$2.0b
PVLA Palvella Therapeutics
8.9x58.26%US$2.2b
SION Sionna Therapeutics
7.1x-12.52%US$2.0b
CLDX Celldex Therapeutics
6.7x45.95%US$3.1b
TSHA Taysha Gene Therapies
9.6x52.48%US$2.1b

Price-To-Book vs Peers: TSHA is good value based on its Price-To-Book Ratio (9.6x) compared to the peer average (29.1x).

Historical Price to Book Ratio

Historical Price to Book Ratio compares a stock's price to the book value of it's equity over time. Higher ratios indicate that investors are willing to pay more for the stock.

Fetching historical data

Price to Book Ratio vs Industry

How does TSHA's PB Ratio compare vs other companies in the US Biotechs Industry?

60 CompaniesPrice / BookEstimated GrowthMarket Cap
CNTN Canton Strategic Holdings
0.4xn/aUS$176.61m
ENGN enGene Therapeutics
0.5x23.99%US$128.62m
ENLV Enlivex
0.06x-147.76%US$118.92m
FRMM Forum Markets
0.5x127.69%US$77.94m
TSHA 9.6xIndustry Avg. 2.7xNo. of Companies83PB0246810+
60 CompaniesEstimated GrowthMarket Cap
No more companies

Price-To-Book vs Industry: TSHA is expensive based on its Price-To-Book Ratio (9.6x) compared to the US Biotechs industry average (2.7x).

Price to Book Ratio vs Fair Ratio

What is TSHA's PB Ratio compared to its Fair PB Ratio? This is the expected PB Ratio taking into account the company's forecast earnings growth, profit margins and other risk factors.

TSHA PB Ratio vs Fair Ratio.
Fair Ratio
Current PB Ratio9.6x
Fair PB Ration/a

Price-To-Book vs Fair Ratio: Insufficient data to calculate TSHA's Price-To-Book Fair Ratio for valuation analysis.

Analyst Price Targets

What is the analyst 12-month forecast and do we have any statistical confidence in the consensus price target?

The above table shows the analyst TSHA forecast and predictions for the stock price in 12 month’s time.
DateShare PriceAverage 1Y Price TargetDispersionHighLow1Y Actual priceAnalysts
CurrentUS$6.34
US$13.00
+105.05%
19.32%US$19.00US$10.00n/a13
Jul ’27US$6.65
US$13.00
+95.49%
19.32%US$19.00US$10.00n/a13
Jun ’27US$5.97
US$12.23
+104.87%
23.38%US$19.00US$8.00n/a13
May ’27US$6.33
US$11.57
+82.80%
27.85%US$19.00US$7.00n/a14
Apr ’27US$4.31
US$11.36
+163.51%
25.91%US$19.00US$7.00n/a14
Mar ’27US$4.53
US$11.00
+142.83%
26.84%US$19.00US$7.00n/a14
Feb ’27US$4.51
US$11.00
+143.90%
26.84%US$19.00US$7.00n/a14
Jan ’27US$5.50
US$10.79
+96.10%
28.29%US$19.00US$7.00n/a14
Dec ’26US$4.43
US$10.54
+137.89%
32.79%US$19.00US$5.00n/a13
Nov ’26US$4.96
US$9.77
+96.96%
28.15%US$14.00US$5.00n/a13
Oct ’26US$3.18
US$8.67
+172.54%
29.16%US$14.00US$5.00n/a12
Sep ’26US$2.92
US$8.67
+196.80%
29.16%US$14.00US$5.00n/a12
Aug ’26US$2.63
US$8.32
+216.28%
25.41%US$13.00US$5.00n/a11
Jul ’26US$2.34
US$8.35
+256.84%
26.52%US$13.00US$5.00US$6.6510
Jun ’26US$2.71
US$7.35
+171.22%
18.27%US$9.00US$5.00US$5.9710
May ’26US$2.41
US$6.77
+181.03%
19.24%US$9.00US$5.00US$6.3311
Apr ’26US$1.27
US$6.55
+417.79%
17.56%US$8.00US$5.00US$4.3110
Mar ’26US$1.60
US$6.59
+311.93%
16.75%US$8.00US$5.00US$4.5311
Feb ’26US$1.50
US$6.59
+339.39%
16.75%US$8.00US$5.00US$4.5111
Jan ’26US$1.73
US$6.59
+280.98%
16.75%US$8.00US$5.00US$5.5011
Dec ’25US$3.24
US$6.59
+103.42%
16.75%US$8.00US$5.00US$4.4311
Nov ’25US$1.53
US$6.41
+318.89%
15.89%US$8.00US$5.00US$4.9611
Oct ’25US$2.02
US$6.41
+217.28%
15.89%US$8.00US$5.00US$3.1811
Sep ’25US$2.24
US$6.41
+186.12%
15.89%US$8.00US$5.00US$2.9211
Aug ’25US$2.16
US$6.59
+205.13%
15.45%US$8.00US$5.00US$2.6311
Jul ’25US$2.26
US$6.59
+191.63%
15.45%US$8.00US$5.00US$2.3411
US$13
Fair Value
51.2% undervalued intrinsic discount
13
Number of Analysts

Analyst Forecast: Target price is more than 20% higher than the current share price, but analysts are not within a statistically confident range of agreement.

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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/07/10 22:04
End of Day Share Price 2026/07/10 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Taysha Gene Therapies, Inc. is covered by 24 analysts. 13 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Jack AllenBaird
Keith TapperBMO Capital Markets Equity Research
Evan SeigermanBMO Capital Markets Equity Research