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Sagimet Biosciences Inc.NasdaqGM:SGMT Stock Report

Market Cap US$423.6m
Share Price
n/a
1Y-10.3%
7D5.7%
1D2.9%
Portfolio Value
​
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Sagimet Biosciences Inc.

NasdaqGM:SGMT Stock Report

Market Cap: US$423.6m

Sagimet Biosciences (SGMT) Stock Overview

A clinical-stage biopharmaceutical company, develops novel therapeutics called fatty acid synthase (FASN) inhibitors for the treatment of diseases that result from dysfunctional metabolic and fibrotic pathways in the United States. More details

SGMT fundamental analysis
Snowflake Score
Valuation1/6
Future Growth2/6
Past Performance0/6
Financial Health6/6
Dividends0/6

Rewards

Revenue is forecast to grow 70.55% per year

Risk Analysis

Shareholders have been substantially diluted in the past year

Makes less than USD$1m in revenue ($0)

Currently unprofitable and not forecast to become profitable over the next 3 years

Volatile share price over the past 3 months compared to the US market


SGMT Community Fair Values

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Sagimet Biosciences Inc. Competitors

Price History & Performance

Summary of share price highs, lows and changes for Sagimet Biosciences
Historical stock prices
Current Share PriceUS$7.06
52 Week HighUS$11.41
52 Week LowUS$4.50
Beta3.44
1 Month Change-2.22%
3 Month Change44.38%
1 Year Change-10.29%
3 Year Changen/a
5 Year Changen/a
Change since IPO-55.74%

Recent News & Updates

Seeking Alpha • May 14

Sagimet Biosciences: Making The Bull Case For Differentiated Denifanstat

Summary Sagimet Biosciences receives a Buy rating, driven by denifanstat's potential in MASH and acne, despite higher risk. Denifanstat met all endpoints in Phase 2b MASH and Phase 3 China acne trials, supporting optimism for US acne Phase 3. SGMT's near-term catalysts include US Phase 3 acne trial initiation and milestone payments from China partner Ascletis. Funding remains a concern, with the cash runway potentially not extending beyond 2027, making clinical and partnership progress critical. Read the full article on Seeking Alpha

Recent updates

Seeking Alpha • May 14

Sagimet Biosciences: Making The Bull Case For Differentiated Denifanstat

Summary Sagimet Biosciences receives a Buy rating, driven by denifanstat's potential in MASH and acne, despite higher risk. Denifanstat met all endpoints in Phase 2b MASH and Phase 3 China acne trials, supporting optimism for US acne Phase 3. SGMT's near-term catalysts include US Phase 3 acne trial initiation and milestone payments from China partner Ascletis. Funding remains a concern, with the cash runway potentially not extending beyond 2027, making clinical and partnership progress critical. Read the full article on Seeking Alpha
Analysis Article • Apr 18

Here's Why We're Not Too Worried About Sagimet Biosciences' (NASDAQ:SGMT) Cash Burn Situation

Just because a business does not make any money, does not mean that the stock will go down. For example, Sagimet...
Analysis Article • Jan 12

We're Hopeful That Sagimet Biosciences (NASDAQ:SGMT) Will Use Its Cash Wisely

We can readily understand why investors are attracted to unprofitable companies. For example, although...
Analysis Article • Mar 19

Sagimet Biosciences (NASDAQ:SGMT) Is In A Good Position To Deliver On Growth Plans

Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...
Seeking Alpha • Mar 07

Sagimet Biosciences' Denifanstat Should Be Worth More Today

Summary Denifanstat is SGMT’s leading FASN inhibitor for MASH. It has shown strong Phase 2b results and earned the FDA Breakthrough Therapy designation. SGMT also has a diversified pipeline on acne, solid tumors, and GBM, enhancing its optionality beyond its primary MASH focus. They’ve recently shown some positive trial milestones, including the first Phase 3 dosing. SGMT’s management estimates that if Denifanstat is approved as a MASH therapy, it could have significant market potential for millions of US patients. In my view, SGMT simply has too many strategic options like partnerships, licensing, or M&A that could unlock its value with Denifanstat in the next few years. Read the full article on Seeking Alpha
Analysis Article • Dec 15

Sagimet Biosciences (NASDAQ:SGMT) Is In A Good Position To Deliver On Growth Plans

Just because a business does not make any money, does not mean that the stock will go down. For example, biotech and...
Seeking Alpha • Nov 14

Sagimet: More Than Just A MASH Drug Development Biotech

Summary Sagimet Biosciences Inc.'s Initiation of the phase 3 FASCINIT and FASCINATE-3 studies, using denifanstat for treatment of patients with MASH/MAFLD & MASH respectively, expected before the end of 2024. The global acne treatment market size is projected to grow from $17.48 billion by 2032. Results from phase 3 study by partner Ascletis, using denifanstat for treatment of patients with Acne Vulgaris, expected by Q2 of 2025. The global non-alcoholic steatohepatitis market expected to reach $39.3 billion by 2031. Read the full article on Seeking Alpha
Seeking Alpha • Oct 18

Sagimet Soars: FDA Breakthrough Therapy Designation And Lancet Review Validate Denifanstat

Summary Sagimet Biosciences' Denifanstat shows significant potential in treating MASH, with FDA Breakthrough Therapy designation and peer-reviewed validation, supporting a "Strong Buy" rating. Denifanstat's unique FASN inhibition mechanism effectively reduces liver fibrosis, positioning it as a superior treatment for advanced MASH compared to competitors like Tirzepatide. SGMT's robust financials, including $188.5 million in liquidity and no debt, provide a solid foundation for advancing Denifanstat through Phase 3 trials. Potential applications in dermatology and oncology, along with favorable safety profiles, enhance Denifanstat's market prospects and underscore SGMT's undervaluation. Read the full article on Seeking Alpha
Seeking Alpha • Jul 31

Sagimet Biosciences' Denifanstat Remains A Strong Buy Despite Eli Lilly's Tirzepatide

Summary Sagimet Biosciences is progressing with Denifanstat research targeting MASH, acne, and cancer with promising Phase 2b trial results. Denifanstat is progressing toward Phase 3 trials, with positive results reinforcing its potential, especially for hepatic-impaired patients. Eli Lilly’s Tirzepatide presents strong competition for Denifanstat in MASH treatment, showing higher efficacy in recent trials. SGMT’s strong cash position and favorable valuation make it an attractive investment despite Eli Lilly's competitive pressures. Denifanstat’s unique safety profile and potential for combination therapies justify a "Strong Buy" rating, targeting niche markets and specific patient populations. Read the full article on Seeking Alpha
Analysis Article • May 31

Companies Like Sagimet Biosciences (NASDAQ:SGMT) Are In A Position To Invest In Growth

Just because a business does not make any money, does not mean that the stock will go down. For example, although...
Seeking Alpha • Apr 26

Sagimet Biosciences' Denifanstat Imminent Phase 3: A Promising Investment Opportunity

Summary Sagimet Biosciences is a clinical-stage biopharmaceutical company researching a cure for metabolic dysfunction-related diseases by inhibiting fatty acid synthase. Revenue generated so far comes from licensing agreements, and no product sales are anticipated in the near future. SGMT's leading drug candidate, denifanstat, is progressing to phase 3 with successful trial results, targeting MASH, a leading cause of liver transplants. SGMT's balance sheet shows a cash runway of about 3.3 years, sufficient for Phase 3 trials. Still, I'm somewhat concerned due to a high rate of TEAEs related to denifanstat. Despite risks associated with clinical trials and adverse events, SGMT is a strong buy with significant upside potential in MASH. Read the full article on Seeking Alpha
Seeking Alpha • Jan 24

Sagimet: Additional Upside Possible After Latest NASH Data Release

Summary Primary endpoints and multiple secondary endpoints met in phase 2b FASCINATE study, using denifanstat for F2-F3 NASH patients with statistical significance. An end of phase 2 meeting and phase 3 trial initiation using denifanstat for the treatment of NASH patients with related fibrosis, is expected in 2024. The global non-alcoholic steatohepatitis market is expected to reach $20 billion by 2029. FASN pathway inhibition can also be used towards treating cancers and dermatological disorders. Read the full article on Seeking Alpha

Shareholder Returns

SGMTUS BiotechsUS Market
7D5.7%7.5%-2.6%
1Y-10.3%40.6%20.0%

Return vs Industry: SGMT underperformed the US Biotechs industry which returned 36.7% over the past year.

Return vs Market: SGMT underperformed the US Market which returned 18.6% over the past year.

Price Volatility

Is SGMT's price volatile compared to industry and market?
SGMT volatility
SGMT Average Weekly Movement14.8%
Biotechs Industry Average Movement10.6%
Market Average Movement7.3%
10% most volatile stocks in US Market16.7%
10% least volatile stocks in US Market3.2%

Stable Share Price: SGMT's share price has been volatile over the past 3 months compared to the US market.

Volatility Over Time: SGMT's weekly volatility (15%) has been stable over the past year, but is still higher than 75% of US stocks.

About the Company

FoundedEmployeesCEOWebsite
200616Dave Happelwww.sagimet.com

Sagimet Biosciences Inc., a clinical-stage biopharmaceutical company, develops novel therapeutics called fatty acid synthase (FASN) inhibitors for the treatment of diseases that result from dysfunctional metabolic and fibrotic pathways in the United States. The company’s lead drug candidate is Denifanstat, an oral, once-daily pill and selective FASN inhibitor for the treatment of metabolic dysfunction-associated steatohepatitis, acne, and select forms of cancer. It also develops TVB-3567, a FASN inhibitor for the treatment of acne indication; and other oncology programs, such as solid tumor and glioblastoma.

Sagimet Biosciences Inc. Fundamentals Summary

How do Sagimet Biosciences's earnings and revenue compare to its market cap?
SGMT fundamental statistics
Market capUS$423.62m
Earnings (TTM)-US$43.51m
Revenue (TTM)n/a
0.0x
P/S Ratio
-10.0x
P/E Ratio

Is SGMT overvalued?

See Fair Value and valuation analysis

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
SGMT income statement (TTM)
RevenueUS$0
Cost of RevenueUS$0
Gross ProfitUS$0
Other ExpensesUS$43.51m
Earnings-US$43.51m

Last Reported Earnings

Mar 31, 2026

Next Earnings Date

n/a

Earnings per share (EPS)-0.70
Gross Margin0.00%
Net Profit Margin0.00%
Debt/Equity Ratio0%

How did SGMT perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/06/26 23:20
End of Day Share Price 2026/06/26 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Sagimet Biosciences Inc. is covered by 12 analysts. 9 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Eliana MerleBarclays
Edward NashCanaccord Genuity
Jonathan WollebenCitizens JMP Securities, LLC