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Milestone Pharmaceuticals Inc.NasdaqGS:MIST Stock Report

Market Cap US$175.5m
Share Price
US$1.31
US$8
83.6% undervalued intrinsic discount
1Y-23.8%
7D7.4%
1D
Portfolio Value
View

Milestone Pharmaceuticals Inc.

NasdaqGS:MIST Stock Report

Market Cap: US$175.5m

Milestone Pharmaceuticals (MIST) Stock Overview

A biopharmaceutical company, focuses on the development and commercialization of cardiovascular medicines in the United States and Canada. More details

MIST fundamental analysis
Snowflake Score
Valuation0/6
Future Growth2/6
Past Performance0/6
Financial Health5/6
Dividends0/6

MIST Community Fair Values

Create Narrative

See what 24 others think this stock is worth. Follow their fair value or set your own to get alerts.

Milestone Pharmaceuticals Inc. Competitors

Price History & Performance

Summary of share price highs, lows and changes for Milestone Pharmaceuticals
Historical stock prices
Current Share PriceUS$1.31
52 Week HighUS$3.06
52 Week LowUS$1.00
Beta0.96
1 Month Change-10.27%
3 Month Change-22.94%
1 Year Change-23.84%
3 Year Change-60.54%
5 Year Change-77.95%
Change since IPO-91.48%

Recent News & Updates

Seeking Alpha Jun 09

Milestone Pharmaceuticals: Here Comes The Revenue Ramp

Summary Milestone Pharmaceuticals Inc. remains a Strong Buy, despite recent volatility and a 37% stock decline since FDA approval of Cardamyst. Cardamyst’s rapid-acting efficacy, expanding insurance coverage, and unique market position underpin a compelling medium-term ramp in prescriptions and revenue. International expansion and a Phase 3 trial for AFib-RVR could significantly enlarge MIST’s addressable market and long-term growth prospects. With net cash, de-risked execution, and negativity priced in, positive insurance or revenue catalysts could drive a sharp MIST stock rebound. Read the full article on Seeking Alpha

Recent updates

Seeking Alpha Jun 09

Milestone Pharmaceuticals: Here Comes The Revenue Ramp

Summary Milestone Pharmaceuticals Inc. remains a Strong Buy, despite recent volatility and a 37% stock decline since FDA approval of Cardamyst. Cardamyst’s rapid-acting efficacy, expanding insurance coverage, and unique market position underpin a compelling medium-term ramp in prescriptions and revenue. International expansion and a Phase 3 trial for AFib-RVR could significantly enlarge MIST’s addressable market and long-term growth prospects. With net cash, de-risked execution, and negativity priced in, positive insurance or revenue catalysts could drive a sharp MIST stock rebound. Read the full article on Seeking Alpha
New Narrative Apr 18

FDA Approval And Shift To Self Administered Care Will Reshape This Cardiovascular Opportunity

Catalysts About Milestone Pharmaceuticals Milestone Pharmaceuticals is a cardiovascular focused company centered on CARDAMYST, an etripamil nasal spray for on demand treatment of paroxysmal supraventricular tachycardia in adults. What are the underlying business or industry changes driving this perspective?
New Narrative Apr 04

Payer Constraints On Self Administered PSVT Care Will Challenge Near Term Progress Yet Offer Upside

Catalysts About Milestone Pharmaceuticals Milestone Pharmaceuticals is a cardiovascular-focused biopharmaceutical company with an FDA approved, self-administered intranasal therapy, CARDAMYST, for acute treatment of paroxysmal supraventricular tachycardia in adults. What are the underlying business or industry changes driving this perspective?
New Narrative Mar 21

Acute Cardiovascular Self Administration Will Reshape Treatment Patterns And Support Long Term Thesis

Catalysts About Milestone Pharmaceuticals Milestone Pharmaceuticals is a biopharmaceutical company focused on developing and commercializing therapies for acute cardiovascular conditions, including paroxysmal supraventricular tachycardia through its intranasal etripamil product, CARDAMYST. What are the underlying business or industry changes driving this perspective?
Analysis Article Nov 15

Does Milestone Pharmaceuticals (NASDAQ:MIST) Have A Healthy Balance Sheet?

David Iben put it well when he said, 'Volatility is not a risk we care about. What we care about is avoiding the...
Analysis Article Nov 06

Does Milestone Pharmaceuticals (NASDAQ:MIST) Have A Healthy Balance Sheet?

Legendary fund manager Li Lu (who Charlie Munger backed) once said, 'The biggest investment risk is not the volatility...
Analysis Article Jun 07

Here's Why Shareholders Should Examine Milestone Pharmaceuticals Inc.'s (NASDAQ:MIST) CEO Compensation Package More Closely

Key Insights Milestone Pharmaceuticals' Annual General Meeting to take place on 13th of June CEO Joe Oliveto's total...
Analysis Article Sep 13

Is Milestone Pharmaceuticals (NASDAQ:MIST) A Risky Investment?

The external fund manager backed by Berkshire Hathaway's Charlie Munger, Li Lu, makes no bones about it when he says...
Analysis Article Mar 07

We're Keeping An Eye On Milestone Pharmaceuticals' (NASDAQ:MIST) Cash Burn Rate

We can readily understand why investors are attracted to unprofitable companies. For example, although Amazon.com made...
Analysis Article Oct 15

We're Keeping An Eye On Milestone Pharmaceuticals' (NASDAQ:MIST) Cash Burn Rate

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although...
Analysis Article Jun 24

We Think Milestone Pharmaceuticals (NASDAQ:MIST) Can Afford To Drive Business Growth

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although...
Analysis Article Feb 25

We're Hopeful That Milestone Pharmaceuticals (NASDAQ:MIST) Will Use Its Cash Wisely

We can readily understand why investors are attracted to unprofitable companies. For example, although...
Analysis Article Aug 25

We're Interested To See How Milestone Pharmaceuticals (NASDAQ:MIST) Uses Its Cash Hoard To Grow

Just because a business does not make any money, does not mean that the stock will go down. For example, biotech and...
Analysis Article Apr 02

Companies Like Milestone Pharmaceuticals (NASDAQ:MIST) Are In A Position To Invest In Growth

We can readily understand why investors are attracted to unprofitable companies. By way of example, Milestone...
Analysis Article Jan 15

What You Need To Know About Milestone Pharmaceuticals Inc.'s (NASDAQ:MIST) Investor Composition

A look at the shareholders of Milestone Pharmaceuticals Inc. ( NASDAQ:MIST ) can tell us which group is most powerful...

Shareholder Returns

MISTUS PharmaceuticalsUS Market
7D7.4%-1.5%2.3%
1Y-23.8%36.8%25.5%

Return vs Industry: MIST underperformed the US Pharmaceuticals industry which returned 36.8% over the past year.

Return vs Market: MIST underperformed the US Market which returned 25.5% over the past year.

Price Volatility

Is MIST's price volatile compared to industry and market?
MIST volatility
MIST Average Weekly Movement13.4%
Pharmaceuticals Industry Average Movement10.2%
Market Average Movement7.2%
10% most volatile stocks in US Market16.8%
10% least volatile stocks in US Market3.1%

Stable Share Price: MIST's share price has been volatile over the past 3 months compared to the US market.

Volatility Over Time: MIST's weekly volatility (13%) has been stable over the past year, but is still higher than 75% of US stocks.

About the Company

FoundedEmployeesCEOWebsite
200338Joe Olivetowww.milestonepharma.com

Milestone Pharmaceuticals Inc., a biopharmaceutical company, focuses on the development and commercialization of cardiovascular medicines in the United States and Canada. It offers CARDAMYST (etripamil) nasal spray, a prescription medication for the conversion of acute symptomatic episodes of paroxysmal supraventricular tachycardia (PSVT) to sinus rhythm in adults. The company is also developing etripamil for the indication of atrial fibrillation with rapid ventricular rate (AFib-RVR).

Milestone Pharmaceuticals Inc. Fundamentals Summary

How do Milestone Pharmaceuticals's earnings and revenue compare to its market cap?
MIST fundamental statistics
Market capUS$175.50m
Earnings (TTM)-US$68.36m
Revenue (TTM)US$1.78m
99.9x
P/S Ratio
-2.6x
P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
MIST income statement (TTM)
RevenueUS$1.78m
Cost of RevenueUS$14.00k
Gross ProfitUS$1.77m
Other ExpensesUS$70.13m
Earnings-US$68.36m

Last Reported Earnings

Mar 31, 2026

Next Earnings Date

n/a

Earnings per share (EPS)-0.50
Gross Margin99.22%
Net Profit Margin-3,832.01%
Debt/Equity Ratio378.1%

How did MIST perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/06/17 00:04
End of Day Share Price 2026/06/17 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Milestone Pharmaceuticals Inc. is covered by 9 analysts. 6 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Patrick TrucchioH.C. Wainwright & Co.
Brandon FolkesH.C. Wainwright & Co.
Christopher HowertonJefferies LLC