Live News • May 20
Halozyme Therapeutics Beats Q1 Revenue Expectations and Launches $1 Billion Share Buyback Halozyme reported Q1 2026 revenue of US$376.7m, up 42.2% year over year and 6.1% above analyst expectations, with diluted EPS of US$1.22 that was below consensus but 31.2% higher than a year ago.
Royalty revenue from the ENHANZE platform rose 43%, supported by wider use of partner drugs such as DARZALEX, VYVGART Hytrulo and PHESGO, while new deals with Vertex, Oruka and GSK extend projected royalty streams into the 2030s and 2040s.
The company reaffirmed its 2026 outlook of about US$1.76b in revenue and adjusted EPS of roughly US$8, announced a US$1b share buyback with at least US$400m planned for this year, and highlighted plans to scale Hypercon manufacturing and start new clinical programs in 2027.
A recent analysis citing 32.2% annual revenue growth over the past two years and 28.7% annual EPS growth over five years states that the stock appears undervalued with an estimated upside of 27.3%.
The combination of strong recent results, long-dated royalty agreements and a sizable buyback indicates management’s confidence in the company’s cash generation and business model.
Investors should weigh that confidence and reported growth track record against typical biotech risks around partner performance, regulatory outcomes and the timing of new clinical programs. Recent Insider Transactions Derivative • May 17
President exercised options and sold US$2.8m worth of stock On the 13th of May, Helen Torley exercised 50k options at a strike price of around US$12.07 and sold these shares for an average price of US$68.68 per share. This trade did not impact their existing holding. For the year to December 2019, Helen's total compensation was 4% salary and 96% other compensation. This indicates that these sales could comprise a meaningful part of their income for the year. Since June 2025, Helen's direct individual holding has increased from 733.72k shares to 767.78k. Company insiders have collectively sold US$44m more than they bought, via options and on-market transactions in the last 12 months. Announcement • May 13
Halozyme Therapeutics, Inc. (NasdaqGS:HALO) announces an Equity Buyback for $1,000 million worth of its shares. Halozyme Therapeutics, Inc. (NasdaqGS:HALO) announces a share repurchase program. Under the program, the company will repurchase up to $1,000 million worth of its shares. The program will be valid till December 31, 2028. Reported Earnings • May 12
First quarter 2026 earnings: Revenues exceed analysts expectations while EPS lags behind First quarter 2026 results: EPS: US$1.27 (up from US$0.96 in 1Q 2025). Revenue: US$376.7m (up 42% from 1Q 2025). Net income: US$150.0m (up 27% from 1Q 2025). Profit margin: 40% (down from 45% in 1Q 2025). Revenue exceeded analyst estimates by 4.9%. Earnings per share (EPS) missed analyst estimates by 4.1%. Revenue is forecast to grow 5.7% p.a. on average during the next 3 years, compared to a 22% growth forecast for the Biotechs industry in the US. Over the last 3 years on average, earnings per share has increased by 28% per year whereas the company’s share price has increased by 29% per year. Announcement • May 12
Halozyme Therapeutics, Inc. Reiterates Its Earnings Guidance for 2026 Halozyme Therapeutics, Inc. reiterated its earnings guidance for 2026. For the period, the company expects total revenue of $1.710 billion to $1.810 billion, representing growth of 22% to 30% over 2025 total revenue, primarily driven by increases in royalty revenue and product sales from API. Announcement • May 03
Halozyme Therapeutics, Inc Announces the Appointment of Darren Snellgrove as Chief Financial Officer, Effective June 8, 2026 Halozyme Therapeutics, Inc. announced the appointment of Darren Snellgrove as Chief Financial Officer, effective June 8, 2026. Mr. Snellgrove will be responsible for leading Halozyme's financial operations and strategy, including capital allocation, corporate development and investor relations. Darren will report to Helen Torley, President and Chief Executive Officer. Mr. Snellgrove brings more than 30 years of exceptional financial leadership, strategic insight, and operational excellence across the biopharmaceutical and medtech sectors. Most recently, he led investor relations at Johnson & Johnson, a Fortune 50 healthcare company. In that role, he reshaped corporate messaging and investor engagement strategies, strengthened analyst and shareholder relationships, and supported strong market performance. Previously, Mr. Snellgrove served as Chief Financial Officer of Johnson & Johnson's Pharmaceuticals sector, where he provided global financial leadership for a business generating more than $50 billion in annual revenue. During his tenure, he delivered impressive financial results, leading large global teams across commercial operations, R&D, supply chain, and business development, and played a central role in major portfolio investments, restructuring initiatives, and business development transactions. Earlier in his career, Mr. Snellgrove held CFO and senior finance leadership roles across pharmaceutical R&D, innovation, and M&A at Johnson & Johnson, as well as progressive finance roles at Centocor prior to its acquisition. Mr. Snellgrove holds an MBA from Villanova University and a BA Honors degree from the University of Southampton in England. Announcement • May 01
Halozyme Therapeutics, Inc. to Report Q1, 2026 Results on May 11, 2026 Halozyme Therapeutics, Inc. announced that they will report Q1, 2026 results After-Market on May 11, 2026 Major Estimate Revision • Apr 30
Consensus EPS estimates fall by 18% The consensus outlook for fiscal year 2026 has been updated. 2026 EPS estimate fell from US$8.55 to US$6.97 per share. Revenue forecast steady at US$1.76b. Net income forecast to grow 165% next year vs 12% decline forecast for Biotechs industry in the US. Consensus price target broadly unchanged at US$85.78. Share price fell 4.4% to US$63.66 over the past week. Recent Insider Transactions Derivative • Apr 07
President exercised options and sold US$2.1m worth of stock On the 2nd of April, Helen Torley exercised 40k options at a strike price of around US$12.07 and sold these shares for an average price of US$64.81 per share. This trade did not impact their existing holding. For the year to December 2019, Helen's total compensation was 4% salary and 96% other compensation. This indicates that these sales could comprise a meaningful part of their income for the year. Since June 2025, Helen's direct individual holding has increased from 733.72k shares to 767.78k. Company insiders have collectively sold US$40m more than they bought, via options and on-market transactions in the last 12 months. Announcement • Mar 24
Halozyme Therapeutics, Inc., Annual General Meeting, May 05, 2026 Halozyme Therapeutics, Inc., Annual General Meeting, May 05, 2026. Recent Insider Transactions • Mar 12
Senior VP & COO recently sold US$495k worth of stock On the 10th of March, Cortney Caudill sold around 7k shares on-market at roughly US$67.64 per share. This transaction amounted to 51% of their direct individual holding at the time of the trade. This was the largest sale by an insider in the last 3 months. This was Cortney's only on-market trade for the last 12 months. Announcement • Mar 12
Halozyme Therapeutics, Inc. Appoints David Ramsay as Interim Chief Financial Officer, Effective March 23, 2026 Halozyme Therapeutics, Inc. announced that David Ramsay has been appointed Interim Chief Financial Officer (CFO), effective March 23, 2026. Mr. Ramsay will oversee all financial operations while the company continues its active search for a permanent CFO. Mr. Ramsay brings more than 30 years of strategic financial leadership across the biotechnology and life sciences sectors, including extensive experience in capital markets, corporate finance, investor relations, and operational scale-up. He previously served as Halozyme's Chief Financial Officer from 2003 to 2009 and again from 2013 to 2015, during which time the company evolved from a private enterprise to a billion-dollar public biopharmaceutical company. During his prior tenure as CFO, Mr. Ramsay guided the company through significant growth and played a key role in establishing Halozyme's foundational financial and technology commercialization infrastructure. Previously, Mr. Ramsay served as Senior Vice President and Chief Financial Officer of Bonti, Inc. until its sale to Allergan plc in October 2018. The company's executive search for a permanent Chief Financial Officer is well underway and progressing. Halozyme has engaged a leading executive search firm to identify candidates who bring the combination of capital markets expertise and strategy. Mr. Ramsay will remain in the role until a permanent CFO is appointed. Mr. Ramsay holds a B.S. in business administration from the University of California, Berkeley and an M.B.A. with a dual major in finance and strategic management from The Wharton School at the University of Pennsylvania. Mr. Ramsay (age 61) has served as a member of the Board of Directors of Savara Inc., a clinical-stage biopharmaceutical company focused on rare respiratory diseases. Since 2017, he has also served on the board of directors of Exuma Biotech, Inc., a privately held biotechnology company. Mr. Ramsay served as Senior Vice President and Chief Financial Officer of Bonti, Inc., a private, clinical stage biotechnology company focused on the development and commercialization of neurotoxin products for therapeutic and aesthetic applications, from February 2018 until its acquisition by Allergan plc in October 2018. Mr. Ramsay previously served as the Company’s Chief Financial Officer from 2003 to 2009 and from 2013 until 2015. He also served as the Company’s Vice President, Corporate Development from 2009 to 2013. Mr. Ramsay began his career at Deloitte & Touche, where he obtained his CPA license. Recent Insider Transactions Derivative • Mar 06
President exercised options and sold US$2.9m worth of stock On the 4th of March, Helen Torley exercised 50k options at a strike price of around US$12.07 and sold these shares for an average price of US$69.52 per share. This trade did not impact their existing holding. For the year to December 2019, Helen's total compensation was 8% salary and 92% other compensation. This indicates that these sales could comprise a meaningful part of their income for the year. Since June 2025, Helen's direct individual holding has increased from 733.72k shares to 767.78k. Company insiders have collectively sold US$37m more than they bought, via options and on-market transactions in the last 12 months. Major Estimate Revision • Feb 24
Consensus EPS estimates increase by 17% The consensus outlook for fiscal year 2026 has been updated. 2026 EPS estimate increased from US$7.44 to US$8.73. Revenue forecast steady at US$1.76b. Net income forecast to grow 213% next year vs 8.2% decline forecast for Biotechs industry in the US. Consensus price target up from US$78.00 to US$84.50. Share price fell 11% to US$70.64 over the past week. New Risk • Feb 19
New minor risk - Earnings quality The company has large one-off items impacting its financial results. One-off items were 43% of the size of the rest of the company's trailing 12-month earnings before tax. This is considered a minor risk. One-off items are incomes or expenses that the company does not expect to repeat in future periods. Examples include profits from the sale of a business or expenses from a restructuring or legal settlements. If the company's reported statutory earnings include a large proportion of one-off items it means they may be an unreliable indicator of its true business performance as the earnings were skewed by these incomes or expenses. Currently, the following risks have been identified for the company: Minor Risks High level of debt (4,097% net debt to equity). Large one-off items impacting financial results. Profit margins are more than 30% lower than last year (23% net profit margin). Reported Earnings • Feb 18
Full year 2025 earnings: EPS misses analyst expectations Full year 2025 results: EPS: US$2.64 (down from US$3.50 in FY 2024). Revenue: US$1.40b (up 38% from FY 2024). Net income: US$316.9m (down 29% from FY 2024). Profit margin: 23% (down from 44% in FY 2024). The decrease in margin was driven by higher expenses. Revenue was in line with analyst estimates. Earnings per share (EPS) missed analyst estimates by 55%. Revenue is forecast to grow 6.7% p.a. on average during the next 3 years, compared to a 19% growth forecast for the Biotechs industry in the US. Over the last 3 years on average, earnings per share has increased by 36% per year but the company’s share price has only increased by 14% per year, which means it is significantly lagging earnings growth. Announcement • Feb 11
Halozyme Therapeutics, Inc. to Report Q4, 2025 Results on Feb 17, 2026 Halozyme Therapeutics, Inc. announced that they will report Q4, 2025 results After-Market on Feb 17, 2026 Recent Insider Transactions Derivative • Feb 06
President exercised options and sold US$3.3m worth of stock On the 5th of February, Helen Torley exercised 50k options at a strike price of around US$12.07 and sold these shares for an average price of US$77.07 per share. This trade did not impact their existing holding. For the year to December 2019, Helen's total compensation was 8% salary and 92% other compensation. This indicates that these sales could comprise a meaningful part of their income for the year. Since March 2025, Helen's direct individual holding has decreased from 733.72k shares to 708.72k. Company insiders have collectively sold US$34m more than they bought, via options and on-market transactions in the last 12 months. Announcement • Dec 09
Halozyme Therapeutics, Inc. Announces Election of Jim Lang to Board of Directors, Effective December 4, 2025 Halozyme Therapeutics, Inc. announced the election of Jim Lang to its Board of Directors. Jim Lang brings more than 30 years of executive leadership experience in healthcare, life sciences, business services and data analytics. Most recently, Mr. Lang served as Chief Executive Officer of EVERSANA, building the leading global provider of commercialization services to the life sciences industry. As CEO, Mr. Lang led the company's growth through the acquisition of over twenty companies, culminating in its merger with Waltz Health in August 2025. Mr. Lang remains on EVERSANA's board. He also formerly served as CEO of Decision Resources Group (DRG), where he transformed DRG into a leading healthcare data and analytics firm through significant expansion and acquisitions. Previously, Mr. Lang was President of Strategic Decision Group, where he expanded the life sciences practice and later sold it to IMS Health (now IQVIA). Mr. Lang currently serves on the board of Biovie, Inc., a clinical-stage biopharmaceutical company, where he chairs both the Audit Committee and the Nominating and Corporate Governance Committee. He also serves on the board of OptimizeRx Corporation, a digital healthcare technology company, acting as chair of the Compensation Committee and as a member of the Nominating and Corporate Governance Committee. Mr. Lang earned his B.S. in Electrical and Computer Engineering from the University of New Hampshire and his MBA from the Tuck School of Business at Dartmouth. Effective date: December 4, 2025. Recent Insider Transactions Derivative • Dec 03
President exercised options and sold US$1.0m worth of stock On the 1st of December, Helen Torley exercised 17k options at a strike price of around US$8.11 and sold these shares for an average price of US$68.92 per share. This trade did not impact their existing holding. For the year to December 2018, Helen's total compensation was 8% salary and 92% other compensation. This indicates that these sales could comprise a meaningful part of their income for the year. Since March 2025, Helen has owned 733.72k shares directly. Company insiders have collectively sold US$30m more than they bought, via options and on-market transactions in the last 12 months. Announcement • Nov 20
Halozyme Therapeutics, Inc. (NasdaqGS:HALO) completed the acquisition of Elektrofi, Inc. Halozyme Therapeutics, Inc. (NasdaqGS:HALO) entered into a definitive agreement to acquire Elektrofi, Inc. for $900 million on September 30, 2025. The consideration comprised of an upfront payment of $750 million and up to three $50 million milestone payments contingent on three separate product regulatory approvals. Halozyme will finance the transaction using its existing cash reserves and credit facility. Following the close of the acquisition, Chase Coffman will become President of Hypercon and will become a member of Halozyme's leadership team. If the Merger Agreement is terminated under certain circumstances, Halozyme will be required to pay Elektrofi a reverse termination fee in cash equal to $36 million.
The Boards of Directors of both Halozyme and Elektrofi have unanimously approved the transaction. The transaction is expected to close in the fourth quarter of 2025, subject to completion of HSR review and other customary closing conditions. The transaction is expected to be less than 5% dilutive to Non-GAAP diluted EPS over medium-term, excluding potential milestone payments related to programs in development, which could offset dilution prior to projected royalty revenue in 2030 and beyond. Halozyme expects its net leverage to be increased to approximately 2X net debt-to-EBITDA immediately following the transaction close and expects to rapidly de-lever in the subsequent quarters.
BofA Securities, Inc. acted as financial advisor for Halozyme Therapeutics, Inc. Michael J. Aiello and Sachin Kohli of Weil, Gotshal & Manges LLP acted as legal advisor for Halozyme Therapeutics, Inc. Centerview Partners LLC acted as financial advisor for Elektrofi, Inc. Russell Franklin and Michael A. Conza of Morgan of Lewis & Bockius LLP acted as legal advisor for Elektrofi, Inc. eShares, Inc. acted as a transfer agent to Halozyme Therapeutics, Inc.
Halozyme Therapeutics, Inc. (NasdaqGS:HALO) completed the acquisition of Elektrofi, Inc. on November 18, 2025. Recent Insider Transactions Derivative • Nov 14
President exercised options and sold US$3.7m worth of stock On the 12th of November, Helen Torley exercised 60k options at a strike price of around US$8.11 and sold these shares for an average price of US$69.47 per share. This trade did not impact their existing holding. For the year to December 2018, Helen's total compensation was 8% salary and 92% other compensation. This indicates that these sales could comprise a meaningful part of their income for the year. Since December 2024, Helen's direct individual holding has increased from 666.74k shares to 733.72k. Company insiders have collectively sold US$29m more than they bought, via options and on-market transactions in the last 12 months. Reported Earnings • Nov 04
Third quarter 2025 earnings: EPS and revenues exceed analyst expectations Third quarter 2025 results: EPS: US$1.50 (up from US$1.08 in 3Q 2024). Revenue: US$354.3m (up 22% from 3Q 2024). Net income: US$175.2m (up 28% from 3Q 2024). Profit margin: 50% (up from 47% in 3Q 2024). The increase in margin was driven by higher revenue. Revenue exceeded analyst estimates by 4.5%. Earnings per share (EPS) also surpassed analyst estimates by 3.1%. Revenue is forecast to grow 12% p.a. on average during the next 3 years, compared to a 21% growth forecast for the Biotechs industry in the US. Over the last 3 years on average, earnings per share has increased by 44% per year but the company’s share price has only increased by 14% per year, which means it is significantly lagging earnings growth. Announcement • Oct 21
Halozyme Therapeutics, Inc. to Report Q3, 2025 Results on Nov 03, 2025 Halozyme Therapeutics, Inc. announced that they will report Q3, 2025 results After-Market on Nov 03, 2025 Announcement • Oct 07
Halozyme Therapeutics, Inc. Announces Appointment of Cortney Caudill as Senior Vice President and Chief Operating Officer, Effective October 1, 2025 On October 1, 2025, Cortney Caudill was appointed as Senior Vice President, Chief Operating Officer of Halozyme Therapeutics, Inc. (the “Company”), effective immediately. Ms. Caudill (age 49) has served as the Company’s Senior Vice President, Chief Operations Officer since October 2023. Prior to joining the Company, from 2019 to October 2023, Ms. Caudill served in roles with increasing responsibility at Aeglea Biotherapeutics, Inc., a biotechnology company, including Vice President of Manufacturing, Senior Vice President, Technical Operations and most recently as Chief Product Officer. From 2002 to 2018, she held operational roles of increasing responsibility at various life sciences companies such as Cambrex Bioscience, Vaxagen, Inc., Genentech, Vetter Pharma International, Samsung Biologics, Baxalta and Eaulife NA. She received her B.S. degree in biology and her B. A degree in psychology from the University of Texas. Recent Insider Transactions Derivative • Oct 05
President exercised options and sold US$3.8m worth of stock On the 3rd of October, Helen Torley exercised 60k options at a strike price of around US$8.11 and sold these shares for an average price of US$71.86 per share. This trade did not impact their existing holding. For the year to December 2018, Helen's total compensation was 8% salary and 92% other compensation. This indicates that these sales could comprise a meaningful part of their income for the year. Since December 2024, Helen's direct individual holding has increased from 666.74k shares to 733.72k. Company insiders have collectively sold US$27m more than they bought, via options and on-market transactions in the last 12 months. Announcement • Oct 01
Halozyme Therapeutics, Inc. (NasdaqGS:HALO) entered into a definitive agreement to acquire Elektrofi, Inc. for $900 million. Halozyme Therapeutics, Inc. (NasdaqGS:HALO) entered into a definitive agreement to acquire Elektrofi, Inc. for $900 million on October 1, 2025. The consideration comprised of an upfront payment of $750 million and up to three $50 million milestone payments contingent on three separate product regulatory approvals. Halozyme will finance the transaction using its existing cash reserves and credit facility.
The Boards of Directors of both Halozyme and Elektrofi have unanimously approved the transaction. The transaction is expected to close in the fourth quarter of 2025, subject to completion of HSR review and other customary closing conditions. The transaction is expected to be less than 5% dilutive to Non-GAAP diluted EPS over medium-term, excluding potential milestone payments related to programs in development, which could offset dilution prior to projected royalty revenue in 2030 and beyond. Halozyme expects its net leverage to be increased to approximately 2X net debt-to-EBITDA immediately following the transaction close and expects to rapidly de-lever in the subsequent quarters.
BofA Securities, Inc. acted as financial advisor for Halozyme Therapeutics, Inc. Weil, Gotshal & Manges LLP acted as legal advisor for Halozyme Therapeutics, Inc. Centerview Partners LLC acted as financial advisor for Elektrofi, Inc. Morgan, Lewis & Bockius LLP acted as legal advisor for Elektrofi, Inc. Recent Insider Transactions Derivative • Sep 04
Independent Director notifies of intention to sell stock Bernadette Connaughton intends to sell 9k shares in the next 90 days after lodging an Intent To Sell Form on the 2nd of September. If the sale is conducted around the recent share price of US$73.15, it would amount to US$646k. Since March 2025, Bernadette's direct individual holding has increased from 40.29k shares to 46.79k. Company insiders have collectively sold US$22m more than they bought, via options and on-market transactions in the last 12 months. Price Target Changed • Aug 19
Price target increased by 7.1% to US$70.56 Up from US$65.89, the current price target is an average from 9 analysts. New target price is approximately in line with last closing price of US$69.98. Stock is up 15% over the past year. The company is forecast to post earnings per share of US$5.35 for next year compared to US$3.50 last year. Recent Insider Transactions Derivative • Aug 14
President exercised options and sold US$3.3m worth of stock On the 13th of August, Helen Torley exercised 60k options at a strike price of around US$8.11 and sold these shares for an average price of US$63.62 per share. This trade did not impact their existing holding. For the year to December 2018, Helen's total compensation was 8% salary and 92% other compensation. This indicates that these sales could comprise a meaningful part of their income for the year. Since September 2024, Helen's direct individual holding has increased from 676.74k shares to 733.72k. Company insiders have collectively sold US$24m more than they bought, via options and on-market transactions in the last 12 months. Reported Earnings • Aug 06
Second quarter 2025 earnings: EPS and revenues exceed analyst expectations Second quarter 2025 results: EPS: US$1.36 (up from US$0.73 in 2Q 2024). Revenue: US$325.7m (up 41% from 2Q 2024). Net income: US$165.2m (up 77% from 2Q 2024). Profit margin: 51% (up from 40% in 2Q 2024). The increase in margin was driven by higher revenue. Revenue exceeded analyst estimates by 14%. Earnings per share (EPS) also surpassed analyst estimates by 29%. Revenue is forecast to grow 11% p.a. on average during the next 3 years, compared to a 18% growth forecast for the Biotechs industry in the US. Over the last 3 years on average, earnings per share has increased by 33% per year but the company’s share price has only increased by 12% per year, which means it is significantly lagging earnings growth. Announcement • Aug 06
Halozyme Therapeutics, Inc. Raises Earnings Guidance for the Full Year 2025 Halozyme Therapeutics, Inc. raised earnings guidance for the full year 2025. For the year, the Company expects: Total revenue of $1,275 million to $1,355 million, representing growth of 26% to 33% over 2024 total revenue, primarily driven by increases in royalty revenue. Revenue from royalties of $825 million to $860 million, representing growth of 44% to 51% over 2024 against previous guidance range of $1,200 Million to $1,280 million. Announcement • Jul 22
Halozyme Therapeutics, Inc. to Report Q2, 2025 Results on Aug 05, 2025 Halozyme Therapeutics, Inc. announced that they will report Q2, 2025 results After-Market on Aug 05, 2025 Recent Insider Transactions Derivative • Jul 11
President exercised options and sold US$2.9m worth of stock On the 10th of July, Helen Torley exercised 60k options at a strike price of around US$8.11 and sold these shares for an average price of US$56.46 per share. This trade did not impact their existing holding. For the year to December 2018, Helen's total compensation was 8% salary and 92% other compensation. This indicates that these sales could comprise a meaningful part of their income for the year. Since September 2024, Helen's direct individual holding has increased from 676.74k shares to 733.72k. Company insiders have collectively sold US$23m more than they bought, via options and on-market transactions in the last 12 months. Recent Insider Transactions Derivative • Jun 25
President exercised options and sold US$2.7m worth of stock On the 24th of June, Helen Torley exercised 60k options at a strike price of around US$8.11 and sold these shares for an average price of US$53.09 per share. This trade did not impact their existing holding. For the year to December 2018, Helen's total compensation was 8% salary and 92% other compensation. This indicates that these sales could comprise a meaningful part of their income for the year. Since September 2024, Helen's direct individual holding has increased from 676.74k shares to 733.72k. Company insiders have collectively sold US$21m more than they bought, via options and on-market transactions in the last 12 months. Announcement • Jun 21
Halozyme Therapeutics, Inc. Announces Argenx Received European Commission Approval for VYVGART® Subcutaneous Injection with ENHANZE® for Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Halozyme Therapeutics, Inc. announced that argenx received European Commission (EC) approval of VYVGART® 1000mg (efgartigimod alfa) developed with ENHANZE®, Halozyme's proprietary recombinant human hyaluronidase enzyme (rHuPH20), for subcutaneous (SC) injection as a monotherapy for the treatment of adult patients with progressive or relapsing active chronic inflammatory demyelinating polyneuropathy (CIDP) after prior treatment with corticosteroids or immunoglobulins. VYVGART is the first and only targeted IgG Fc-antibody fragment for Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) and the first novel mechanism of action for CIDP treatment in more than 30 years. The EC decision is based on positive results from the ADHERE clinical trial, the largest study of CIDP patients to date. For more information on the study and its findings, please view argenx's press release issued on June 20, 2025. The approval by the EC is valid in all 27 European Union (EU) Member States, as well as Iceland, Norway and Liechtenstein. Valuation Update With 7 Day Price Move • May 13
Investor sentiment deteriorates as stock falls 15% After last week's 15% share price decline to US$50.23, the stock trades at a forward P/E ratio of 10x. Average trailing P/E is 17x in the Biotechs industry in the US. Total returns to shareholders of 13% over the past three years. Reported Earnings • May 07
First quarter 2025 earnings: EPS and revenues exceed analyst expectations First quarter 2025 results: EPS: US$0.96 (up from US$0.60 in 1Q 2024). Revenue: US$264.9m (up 35% from 1Q 2024). Net income: US$118.1m (up 54% from 1Q 2024). Profit margin: 45% (up from 39% in 1Q 2024). The increase in margin was driven by higher revenue. Revenue exceeded analyst estimates by 15%. Earnings per share (EPS) also surpassed analyst estimates by 51%. Revenue is forecast to grow 12% p.a. on average during the next 3 years, compared to a 18% growth forecast for the Biotechs industry in the US. Over the last 3 years on average, earnings per share has increased by 19% per year whereas the company’s share price has increased by 22% per year. Announcement • Apr 11
Halozyme Therapeutics, Inc. Announces FDA Approval of argenx's VYVGART® Hytrulo Prefilled Syringe Co-Formulated with ENHANZE® for Self-Injection for Generalized Myasthenia Gravis and Chronic Inflammatory Demyelinating Polyneuropathy Halozyme Therapeutics, Inc. announced that argenx has received U.S. Food and Drug Administration (FDA) approval of VYVGART®? Hytrulo prefilled syringe for self-injection (efgartigimod alfa and hyaluronidase-qvFC) for the treatment of adult patients with generalized myasthenia gravis (gMG) who are anti-acetylcholine receptor (AChR) antibody positive and adult patients with chronic inflammatory demyelinating polyneuropathy (CIDP). VYVGART®?Hytrulo prefilled syringe For self-injection is approved as a 20-to-30-second subcutaneous injection administered by a patient, caregiver, or healthcare professional. Patients are able to self-inject after proper instruction in subcutaneous injection technique. The single dose prefilled subcutaneous injection was developed as part of argenx's exclusive partnership with Halozyme on their ENHANZE®? drug delivery technology, which enables rapid, high-volume delivery of biologics. The approval of VYVGART™? Hytrulo prefilled Syringe for self-injection is supported by data from studies evaluating its bioequivalence to VYVGART®? hytrulo in a vial. In addition, human factors validation studies demonstrated that participants with gMG or CIDP, or their caregivers, safely and successfully prepared and administered VYVGART®?™? Hytrulo with the prefilled syringe. Previous FDA approval of VYVGARTTM Hytrulo for patients with gMG and CIDP was based on the global Phase 3 ADAPT, ADAPT-SC and ADHERE trials. Announcement • Mar 22
Halozyme Therapeutics, Inc. Announces the Retirement of Michael J. LaBarre as Senior Vice President, Chief Technical Officer On March 17, 2025, Michael J. LaBarre, Senior Vice President, Chief Technical Officer of Halozyme Therapeutics, Inc. notified the Company of his decision to retire from the Company, effective March 17, 2025. Announcement • Mar 19
Halozyme Therapeutics, Inc., Annual General Meeting, May 01, 2025 Halozyme Therapeutics, Inc., Annual General Meeting, May 01, 2025. Recent Insider Transactions Derivative • Feb 19
President exercised options and sold US$3.9m worth of stock On the 16th of February, Helen Torley exercised options to acquire 66k shares at no cost and sold these for an average price of US$58.29 per share. This trade did not impact their existing holding. For the year to December 2018, Helen's total compensation was 8% salary and 92% other compensation. This indicates that these sales could comprise a meaningful part of their income for the year. Since March 2024, Helen's direct individual holding has decreased from 676.74k shares to 666.74k. Company insiders have collectively sold US$21m more than they bought, via options and on-market transactions in the last 12 months. Announcement • Feb 19
Halozyme Therapeutics, Inc. Reiterates Earnings Guidance for 2025 Halozyme Therapeutics, Inc. reiterated earnings guidance for 2025, which was initially provided on January 8, 2025. For the full year 2025, the Company expects: Total revenue of $1,150 million to $1,225 million, representing growth of 13% to 21% over 2024 total revenue, primarily driven by increases in royalty revenue and product sales from XYOSTED®. Revenue from royalties of $725 million to $750 million, representing growth of 27% to 31% over 2024. Announcement • Feb 15
Connie L. Matsui Announces Not to Stand for Re-Election to the Board of Halozyme Therapeutics, Inc On February 11, 2025, Connie L. Matsui, a member of the Board of Directors of Halozyme Therapeutics, Inc. notified the Company of her intention not to stand for reelection at the Company’s 2025 annual meeting of stockholders. The Company’s management and the Board of Directors would like to thank Ms. Matsui for her nearly 18 years of providing sage advice to the Company. Ms. Matsui’s resignation was not the result of any disagreement with the Company, any matter related to the Company’s operations, policies, practices or strategy, the Company’s management or the Board of Directors. Announcement • Feb 04
Halozyme Therapeutics, Inc. to Report Q4, 2024 Results on Feb 18, 2025 Halozyme Therapeutics, Inc. announced that they will report Q4, 2024 results on Feb 18, 2025 Valuation Update With 7 Day Price Move • Nov 21
Investor sentiment deteriorates as stock falls 15% After last week's 15% share price decline to US$45.70, the stock trades at a forward P/E ratio of 11x. Average trailing P/E is 17x in the Biotechs industry in the US. Total returns to shareholders of 30% over the past three years.