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CSL: Share Price Correction Will Present Opportunity As Vaccine Uncertainty Eases

Published
23 Feb 25
Updated
04 Nov 25
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AnalystConsensusTarget's Fair Value
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1Y
-36.7%
7D
-0.04%

Author's Valuation

AU$246.4927.2% undervalued intrinsic discount

AnalystConsensusTarget Fair Value

Last Update 04 Nov 25

Fair value Decreased 12%

CSL's analyst price target has been lowered from A$280.61 to A$246.49, reflecting analysts' revised expectations following recent updates about weaker revenue growth, a more cautious profit margin outlook, and continued challenges in key business units.

Analyst Commentary

Market analysts have offered mixed perspectives on CSL following recent trading updates and management commentary, resulting in shifts in both ratings and price targets. Their feedback centers on the company's growth drivers, execution risks, and the market’s current valuation of CSL's business prospects.

Bullish Takeaways
  • Bullish analysts note that the recent share price decline following guidance adjustments has created a more attractive entry point, as the valuation now reflects much of the near-term uncertainty.
  • Some view the downgrade to profit expectations as an exaggerated response, with core business fundamentals and long-term market opportunities remaining intact.
  • The decision to defer a potential vaccine demerger is seen positively by some analysts because it could preserve value and provide flexibility until market conditions improve.
  • Despite cautious near-term outlooks, there is a belief among bullish analysts that current levels offer an opportunity for investors to re-engage with a high-quality market leader.
Bearish Takeaways
  • Bearish analysts remain concerned about ongoing revenue headwinds, particularly from the vaccine segment, where U.S. vaccination rates have not rebounded as expected.
  • Cautious profit margin guidance and softer revenue growth forecasts point to operational challenges, which could affect earnings in the coming quarters.
  • The indefinite postponement of the vaccine demerger introduces additional uncertainty, potentially limiting near-term catalysts for outperformance.
  • Some are wary of repeatedly lowered estimates and suggest a wait-and-see approach until evidence of sustained improvement in key business divisions appears.

What's in the News

  • CSL has revised its earnings guidance for financial year 2026, lowering expected revenue growth to 2% to 3% from the previous range of 4% to 5%. (Key Developments)
  • Ken Lim, the current Chief Strategy Officer, will succeed Joy Linton as Chief Financial Officer effective October 7, 2025. This change is aimed at ensuring a smooth leadership transition. (Key Developments)
  • CSL entered into a strategic collaboration with VarmX to fund late-stage development and commercialization of VMX-C001, a potential treatment for restoring blood coagulation in patients on FXa DOACs. (Key Developments)
  • Health Canada has granted marketing authorization for ANDEMBRY (garadacimab), expanding CSL's range of therapies for hereditary angioedema. (Key Developments)

Valuation Changes

  • Consensus Analyst Price Target: Lowered significantly from A$280.61 to A$246.49, indicating moderated expectations for future valuation.
  • Discount Rate: Increased slightly from 6.76% to 6.81%. This reflects higher perceived risk or a greater required return.
  • Revenue Growth: Reduced from 5.30% to 4.39%, pointing to more modest assumptions for topline expansion.
  • Net Profit Margin: Decreased from 22.63% to 21.82%, suggesting expectations of tighter profitability.
  • Future P/E: Declined from 26.1x to 24.6x, signaling a lower multiple applied to projected earnings.

Key Takeaways

  • Operational transformation and investment in innovation are expected to drive margin expansion, earnings growth, and faster introduction of high-value therapies.
  • Market expansion, a focused business structure, and strong demand for plasma and specialty products support sustainable top-line growth and premium positioning.
  • Revenue and margin growth are threatened by market competition, regulatory risks, high costs, slow new product uptake, and execution challenges from restructuring efforts.

Catalysts

About CSL
    Engages in the research, development, manufacture, marketing and distribution of biopharmaceutical products and vaccines in Australia, the United States, Germany, the United Kingdom, Switzerland, China, Hong Kong, and internationally.
What are the underlying business or industry changes driving this perspective?
  • CSL is undertaking significant operational transformation initiatives, targeting over $0.5 billion in cost savings by FY28, focusing on increased efficiency in plasma collection, manufacturing, and R&D, which should expand margins and support stronger net earnings growth as these benefits are realized.
  • The company is leveraging advances in biotechnology-with a refreshed late-stage pipeline (including gene therapies and high-margin products like ANDEMBRY and HEMGENIX)-and plans to reinvest around half of cost savings into innovation and clinical development, potentially accelerating top-line revenue growth from new product launches benefiting from increased acceptance and effectiveness of biologic and precision therapies.
  • CSL expects robust long-term demand in its core plasma and specialty franchises, supported by the rising prevalence of chronic diseases and global population aging, positioning the business for sustainable revenue growth as these demographic health trends continue to expand the addressable market.
  • The demerger of Seqirus is expected to unlock simplification and focus for both resulting companies, enhancing capital allocation, speed of decision-making, and driving revenue and earnings growth through greater business agility and independent strategic execution.
  • Ongoing geographic expansion and market development (e.g., growth in China and new market entry for products like FLUAD and Ferinject) are capitalizing on rising global healthcare spending and broadening access, which should underpin future revenue growth and further support the company's premium pricing power and margin trajectory.

CSL Earnings and Revenue Growth

CSL Future Earnings and Revenue Growth

Assumptions

How have these above catalysts been quantified?
  • Analysts are assuming CSL's revenue will grow by 5.3% annually over the next 3 years.
  • Analysts assume that profit margins will increase from 19.3% today to 22.9% in 3 years time.
  • Analysts expect earnings to reach $4.2 billion (and earnings per share of $8.67) by about September 2028, up from $3.0 billion today. However, there is some disagreement amongst the analysts with the more bullish ones expecting earnings as high as $4.7 billion.
  • In order for the above numbers to justify the analysts price target, the company would need to trade at a PE ratio of 26.2x on those 2028 earnings, up from 21.8x today. This future PE is greater than the current PE for the AU Biotechs industry at 21.8x.
  • Analysts expect the number of shares outstanding to remain consistent over the next 3 years.
  • To value all of this in today's terms, we will use a discount rate of 6.57%, as per the Simply Wall St company report.

CSL Future Earnings Per Share Growth

CSL Future Earnings Per Share Growth

Risks

What could happen that would invalidate this narrative?
  • Intensifying price competition and non-regrettable tender losses in key plasma and iron markets, alongside increased international generic activity, pose sustained risks to both top-line revenue growth and gross margins, particularly as the company deliberately chooses not to chase lower-margin contracts.
  • Slower-than-expected uptake of new product launches (e.g., ANDEMBRY, HEMGENIX) and R&D pipeline setbacks, combined with discontinued or delayed clinical programs, could undermine both revenue acceleration and long-term earnings growth.
  • Persistent cost pressures-particularly related to plasma collection (donor compensation, labor costs, fixed cost absorption from underperforming centers), combined with slower realization of planned cost reductions, threaten to compress net margins if not adequately offset by price or efficiency gains.
  • Heightened regulatory and policy risks, such as the implementation of Medicare Part D reform, Most Favored Nation (MFN) pricing, or potential sector-specific tariffs, may restrict CSL's pricing power or directly reduce U.S. revenues and earnings.
  • Demerger of Seqirus and ongoing organizational restructuring introduce significant execution risk, including one-off restructuring costs and long transition timelines for cost savings, which may constrain near-to-medium-term net profit and create uncertainty around future earnings stability.

Valuation

How have all the factors above been brought together to estimate a fair value?
  • The analysts have a consensus price target of A$284.792 for CSL based on their expectations of its future earnings growth, profit margins and other risk factors. However, there is a degree of disagreement amongst analysts, with the most bullish reporting a price target of A$316.67, and the most bearish reporting a price target of just A$225.54.
  • In order for you to agree with the analyst's consensus, you'd need to believe that by 2028, revenues will be $18.1 billion, earnings will come to $4.2 billion, and it would be trading on a PE ratio of 26.2x, assuming you use a discount rate of 6.6%.
  • Given the current share price of A$206.62, the analyst price target of A$284.79 is 27.4% higher.
  • We always encourage you to reach your own conclusions though. So sense check these analyst numbers against your own assumptions and expectations based on your understanding of the business and what you believe is probable.

How well do narratives help inform your perspective?

Disclaimer

AnalystConsensusTarget is a tool utilizing a Large Language Model (LLM) that ingests data on consensus price targets, forecasted revenue and earnings figures, as well as the transcripts of earnings calls to produce qualitative analysis. The narratives produced by AnalystConsensusTarget are general in nature and are based solely on analyst data and publicly-available material published by the respective companies. These scenarios are not indicative of the company's future performance and are exploratory in nature. Simply Wall St has no position in the company(s) mentioned. Simply Wall St may provide the securities issuer or related entities with website advertising services for a fee, on an arm's length basis. These relationships have no impact on the way we conduct our business, the content we host, or how our content is served to users. The price targets and estimates used are consensus data, and do not constitute a recommendation to buy or sell any stock, and they do not take account of your objectives, or your financial situation. Note that AnalystConsensusTarget's analysis may not factor in the latest price-sensitive company announcements or qualitative material.

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