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Crinetics Pharmaceuticals, Inc.NasdaqGS:CRNX Stock Report

Market Cap US$3.7b
Share Price
US$35.55
US$82.43
56.9% undervalued intrinsic discount
1Y16.5%
7D-3.4%
1D
Portfolio Value
View

Crinetics Pharmaceuticals, Inc.

NasdaqGS:CRNX Stock Report

Market Cap: US$3.7b

Crinetics Pharmaceuticals (CRNX) Stock Overview

A clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors. More details

CRNX fundamental analysis
Snowflake Score
Valuation3/6
Future Growth2/6
Past Performance0/6
Financial Health5/6
Dividends0/6

CRNX Community Fair Values

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See what 9 others think this stock is worth. Follow their fair value or set your own to get alerts.

Crinetics Pharmaceuticals, Inc. Competitors

Price History & Performance

Summary of share price highs, lows and changes for Crinetics Pharmaceuticals
Historical stock prices
Current Share PriceUS$35.55
52 Week HighUS$57.99
52 Week LowUS$25.83
Beta0.28
1 Month Change-8.89%
3 Month Change-12.61%
1 Year Change16.52%
3 Year Change61.52%
5 Year Change109.86%
Change since IPO45.04%

Recent News & Updates

Analysis Article May 13

Industry Analysts Just Upgraded Their Crinetics Pharmaceuticals, Inc. (NASDAQ:CRNX) Revenue Forecasts By 11%

Crinetics Pharmaceuticals, Inc. ( NASDAQ:CRNX ) shareholders will have a reason to smile today, with the analysts...

Recent updates

Analysis Article May 13

Industry Analysts Just Upgraded Their Crinetics Pharmaceuticals, Inc. (NASDAQ:CRNX) Revenue Forecasts By 11%

Crinetics Pharmaceuticals, Inc. ( NASDAQ:CRNX ) shareholders will have a reason to smile today, with the analysts...
Seeking Alpha Oct 30

Crinetics Pharmaceuticals: Its Post-FDA Approval Future

Summary Crinetics Pharmaceuticals (CRNX) stock has surged after FDA approval of Palsonify for acromegaly, unlocking a potential $1.5–$2.2B market and future label expansion. Palsonify offers superior efficacy and convenience versus competitors, positioning CRNX for rapid adoption despite a crowded treatment landscape and modest patient numbers. Pipeline includes atumelnant for CAH and Cushing’s, with pivotal trials starting in late 2025, but faces competition from Neurocrine’s Crenessity. An analysis around Crinetics Pharmaceuticals follows in the paragraphs below. Read the full article on Seeking Alpha
Analysis Article Jun 17

A Look At The Intrinsic Value Of Crinetics Pharmaceuticals, Inc. (NASDAQ:CRNX)

Key Insights The projected fair value for Crinetics Pharmaceuticals is US$37.65 based on 2 Stage Free Cash Flow to...
Analysis Article Apr 23

Crinetics Pharmaceuticals (NASDAQ:CRNX) Is In A Good Position To Deliver On Growth Plans

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although Amazon.com...
Seeking Alpha Jan 02

Crinetics Pharmaceuticals: Attractive Speculative Bet On Market Weakness

Summary Crinetics Pharmaceuticals is currently overvalued but holds strong Wall Street support with a $75.07 average price target, indicating a 47.43% upside. The FDA accepted Crinetics' NDA for paltusotine, setting a PDUFA date of 09/24/2025. Crinetics is preparing for a fall 2025 launch of paltusotine, engaging with payers and endocrinologists to ensure broad patient access and formulary placement. Despite its valuation, Crinetics' advancements in acromegaly treatment and strong Wall Street backing make it a hold and potential acquisition on pullbacks. Read the full article on Seeking Alpha
Analysis Article Oct 02

We're Hopeful That Crinetics Pharmaceuticals (NASDAQ:CRNX) Will Use Its Cash Wisely

Just because a business does not make any money, does not mean that the stock will go down. For example, although...
Seeking Alpha Aug 12

Crinetics Pharmaceuticals: Stop, Look, And Listen Before Buying This High-Priced Clinical Stage Biotech

Summary Paltusotine in the treatment of acromegaly is Crinetics lead therapy with NDA filing planned in H2 2024. Crinetics has no approved drug and its lead therapy will face significant competition once approved. Investors should be aware of the high-risk nature of investing in Crinetics Pharmaceuticals. Read the full article on Seeking Alpha
Analysis Article Jun 01

Most Shareholders Will Probably Agree With Crinetics Pharmaceuticals, Inc.'s (NASDAQ:CRNX) CEO Compensation

Key Insights Crinetics Pharmaceuticals to hold its Annual General Meeting on 7th of June Salary of US$614.0k is part of...
Seeking Alpha May 23

Crinetics: Earlier Data Release For CAH Treatment Bodes Well For Upcoming Conference Data

Summary Positive data released from 4 patients from phase 2 study that took Atumelnant for congenital adrenal hyperplasia, showing reductions in key biomarkers of A4 and 17-OHP. An NDA submission of Paltusotine for the treatment of patients with Acromegaly expected in the 2nd half of 2024. Additional results from phase 2 open-label study, using Atumelnant for patients with CAH, to be presented at ENDO Conference on June 3rd 2024 at 12:00 to 1:30 p.m. ET. Pending positive talks with FDA, possible initiation of phase 3 study using Paltusotine for the treatment of patients with Carcinoid Syndrome by end of 2024. Read the full article on Seeking Alpha

Shareholder Returns

CRNXUS PharmaceuticalsUS Market
7D-3.4%0.1%1.6%
1Y16.5%41.1%28.5%

Return vs Industry: CRNX underperformed the US Pharmaceuticals industry which returned 41.1% over the past year.

Return vs Market: CRNX underperformed the US Market which returned 28.5% over the past year.

Price Volatility

Is CRNX's price volatile compared to industry and market?
CRNX volatility
CRNX Average Weekly Movement7.0%
Pharmaceuticals Industry Average Movement9.8%
Market Average Movement7.2%
10% most volatile stocks in US Market16.8%
10% least volatile stocks in US Market3.0%

Stable Share Price: CRNX has not had significant price volatility in the past 3 months compared to the US market.

Volatility Over Time: CRNX's weekly volatility (7%) has been stable over the past year.

About the Company

FoundedEmployeesCEOWebsite
2008594R. Strutherswww.crinetics.com

Crinetics Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors. The company’s lead product candidate is Paltusotine, an oral selective nonpeptide somatostatin receptor type 2 agonist, which is in a Phase 3 clinical trial for the treatment of acromegaly and carcinoid syndrome associated with neuroendocrine tumors. It is also developing Atumelnant, an investigational oral nonpeptide product candidate to antagonize the adrenocorticotrophic hormone (ACTH) receptor that has completed a Phase 1 study for the treatment of diseases caused by excess ACTH, including congenital adrenal hyperplasia and cushing’s disease; and CRN09682, a nonpeptide drug conjugate for SST2 positive solid tumors.

Crinetics Pharmaceuticals, Inc. Fundamentals Summary

How do Crinetics Pharmaceuticals's earnings and revenue compare to its market cap?
CRNX fundamental statistics
Market capUS$3.75b
Earnings (TTM)-US$496.39m
Revenue (TTM)US$18.07m
207.4x
P/S Ratio
-7.6x
P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
CRNX income statement (TTM)
RevenueUS$18.07m
Cost of RevenueUS$357.18m
Gross Profit-US$339.11m
Other ExpensesUS$157.28m
Earnings-US$496.39m

Last Reported Earnings

Mar 31, 2026

Next Earnings Date

n/a

Earnings per share (EPS)-4.71
Gross Margin-1,876.73%
Net Profit Margin-2,747.18%
Debt/Equity Ratio0%

How did CRNX perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/05/31 12:26
End of Day Share Price 2026/05/29 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Crinetics Pharmaceuticals, Inc. is covered by 21 analysts. 13 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Brian SkorneyBaird
Joshua SchimmerCantor Fitzgerald & Co.
David LebowitzCitigroup Inc