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Oruka Therapeutics, Inc.NasdaqGM:ORKA Stock Report

Market Cap US$6.9b
Share Price
n/a
1Y600.6%
7D10.5%
1D2.6%
Portfolio Value
View

Oruka Therapeutics, Inc.

NasdaqGM:ORKA Stock Report

Market Cap: US$6.9b

Oruka Therapeutics (ORKA) Stock Overview

A clinical-stage biopharmaceutical company, focuses on developing novel monoclonal antibody therapeutics for psoriasis (PsO), and other inflammatory and immunology (I&I) indications. More details

ORKA fundamental analysis
Snowflake Score
Valuation1/6
Future Growth0/6
Past Performance0/6
Financial Health6/6
Dividends0/6

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Oruka Therapeutics, Inc. Competitors

Price History & Performance

Summary of share price highs, lows and changes for Oruka Therapeutics
Historical stock prices
Current Share PriceUS$107.40
52 Week HighUS$109.42
52 Week LowUS$14.03
Beta0
1 Month Change27.01%
3 Month Change68.08%
1 Year Change600.59%
3 Year Changen/a
5 Year Changen/a
Change since IPO272.92%

Recent News & Updates

Seeking Alpha Aug 03

Oruka Therapeutics Is Priced For Perfection - It's Time To Cash Out

Summary Oruka Therapeutics current valuation far exceeds risk-adjusted fundamentals. ORKA's lead assets, ORKA-001 and ORKA-002, are not expected to launch until 2031–2033, just as patents on several competing drugs begin to expire. Sum-of-the-parts analysis yields a $57.8/share valuation, about 40% below ORKA's current $96.51 price. There's minimal upside but major downside risk if clinical trial results underwhelm. Read the full article on Seeking Alpha

Recent updates

Seeking Alpha Aug 03

Oruka Therapeutics Is Priced For Perfection - It's Time To Cash Out

Summary Oruka Therapeutics current valuation far exceeds risk-adjusted fundamentals. ORKA's lead assets, ORKA-001 and ORKA-002, are not expected to launch until 2031–2033, just as patents on several competing drugs begin to expire. Sum-of-the-parts analysis yields a $57.8/share valuation, about 40% below ORKA's current $96.51 price. There's minimal upside but major downside risk if clinical trial results underwhelm. Read the full article on Seeking Alpha

Shareholder Returns

ORKAUS BiotechsUS Market
7D10.5%4.5%1.0%
1Y600.6%38.3%18.4%

Return vs Industry: ORKA exceeded the US Biotechs industry which returned 41.3% over the past year.

Return vs Market: ORKA exceeded the US Market which returned 19% over the past year.

Price Volatility

Is ORKA's price volatile compared to industry and market?
ORKA volatility
ORKA Average Weekly Movement10.1%
Biotechs Industry Average Movement10.0%
Market Average Movement7.2%
10% most volatile stocks in US Market16.2%
10% least volatile stocks in US Market3.1%

Stable Share Price: ORKA has not had significant price volatility in the past 3 months compared to the US market.

Volatility Over Time: ORKA's weekly volatility (10%) has been stable over the past year.

About the Company

FoundedEmployeesCEOWebsite
n/a68Lawrence Kleinorukatx.com

Oruka Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing novel monoclonal antibody therapeutics for psoriasis (PsO), and other inflammatory and immunology (I&I) indications. Its lead products include ORKA-001 that targets p19 subunit of interleukin-23, which is in phase 2a trial for the treatment of PsO; and ORKA-002 that targets interleukin-17A and interleukin-17F, which is in phase 2 trial for the treatment of PsO, psoriatic arthritis, and other conditions. The company also develops ORKA-003 for targeting an undisclosed pathway; and ORKA-021, a sequential combination regimen of ORKA-002 and ORKA-001.

Oruka Therapeutics, Inc. Fundamentals Summary

How do Oruka Therapeutics's earnings and revenue compare to its market cap?
ORKA fundamental statistics
Market capUS$6.93b
Earnings (TTM)-US$109.69m
Revenue (TTM)n/a
0.0x
P/S Ratio
-64.8x
P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
ORKA income statement (TTM)
RevenueUS$0
Cost of RevenueUS$0
Gross ProfitUS$0
Other ExpensesUS$109.69m
Earnings-US$109.69m

Last Reported Earnings

Jun 30, 2026

Next Earnings Date

n/a

Earnings per share (EPS)-1.66
Gross Margin0.00%
Net Profit Margin0.00%
Debt/Equity Ratio0%

How did ORKA perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/08/12 07:24
End of Day Share Price 2026/08/12 00:00
Earnings2026/06/30
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Oruka Therapeutics, Inc. is covered by 14 analysts. 9 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Etzer DaroutBarclays
Julian HarrisonBTIG
Yatin SunejaGuggenheim Securities, LLC