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Precigen, Inc.NasdaqGS:PGEN Stock Report

Market Cap US$1.6b
Share Price
US$4.15
US$8.5
51.2% undervalued intrinsic discount
1Y207.4%
7D-0.2%
Portfolio Value
View

Precigen, Inc.

NasdaqGS:PGEN Stock Report

Market Cap: US$1.6b

Precigen (PGEN) Stock Overview

A discovery and clinical-stage biopharmaceutical company, develops gene and cell therapies using precision technology to target diseases in areas of immuno-oncology, autoimmune disorders, and infectious diseases. More details

PGEN fundamental analysis
Snowflake Score
Valuation2/6
Future Growth6/6
Past Performance0/6
Financial Health4/6
Dividends0/6

PGEN Community Fair Values

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Precigen, Inc. Competitors

Price History & Performance

Summary of share price highs, lows and changes for Precigen
Historical stock prices
Current Share PriceUS$4.15
52 Week HighUS$5.47
52 Week LowUS$1.23
Beta1.07
1 Month Change0.73%
3 Month Change-3.26%
1 Year Change207.41%
3 Year Change264.04%
5 Year Change-35.16%
Change since IPO-83.22%

Recent News & Updates

Recent updates

Seeking Alpha Mar 26

Precigen: The Best Potential Blockbuster You've Never Heard Of (Your ENT Has)

Summary Precigen maintains a Buy rating as Papzimeos' strong launch and FDA approval signal blockbuster potential, with Q1 revenues expected to exceed $18M. PGEN's management guides for cash flow breakeven in 2026, supported by robust payer acceptance and a Q1 revenue run rate over $70M. Scenario analysis yields a probability-weighted fair value of $6.13/share, over 50% above current levels, with a base case fair value of $7.01/share. Key risks include potential Q1 pent-up demand, underestimated competition from Inovio, and overestimated ex-US reimbursement for Papzimeos. Read the full article on Seeking Alpha
Seeking Alpha Feb 28

Precigen: UltraCAR-T Development Brings Another Side Of Pipeline Advancement

Summary BLA of PRGN-2012 for patients with Recurrent Respiratory Papillomatosis was accepted by FDA with a Priority Review date of August 27th of 2025. Marketing approval of PRGN-2012 for RRP would be huge because there is no FDA approved drugs for RRP. Also, there are an estimated 27,000 people in the United States who have it. PGEN is looking to form a strategic partnership or collaboration agreement to advance its UltraCAR-Ts. This technology is crucial because it could change CAR-T landscape for the better. PRGN-3006 is an UltraCAR-T being developed to target patients with Acute Myeloid Leukemia; PRGN-3008 is an UltraCAR-T targeting patients with CD19 solid tumors and autoimmune disorders. Read the full article on Seeking Alpha
Seeking Alpha Feb 10

Precigen: Successful Proof Of Platform, But Cash Worries Remain

Summary Precigen's lead asset, PRGN-2012, shows promising results in treating Recurrent Respiratory Papillomatosis, achieving a 51% complete response rate and reducing surgical interventions. Financially, Precigen has a market cap of $468mn and a cash runway into 2026, but needs more funds for commercialization. The company is prioritizing PRGN-2012's development, restructuring operations, and cutting 20% of its workforce to extend its cash runway. Despite financial risks, Precigen's proven platforms and promising data make it a potential worthwhile investment, pending resolution of cash issues. Read the full article on Seeking Alpha
Analysis Article Feb 28

We're Keeping An Eye On Precigen's (NASDAQ:PGEN) Cash Burn Rate

Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...
Seeking Alpha Jan 20

Precigen: RRP Targeting With AdenoVerse Technology Platform

Summary FDA agreed to allow phase 1/2 study to serve as the basis for being able to file for Accelerated Approval of PRGN-2012 for the treatment of patients with recurrent respiratory papillomatosis. A BLA filing of PRGN-2012 for the treatment of patients with recurrent respiratory papillomatosis is expected in the 2nd half of 2024. It is projected that it could earn $2 billion in peak sales globally of PRGN-2012 for the treatment of patients with recurrent respiratory papillomatosis. PRGN-2009 which also uses the AdenoVerse technology has one phase 2 study targeting OPSCC underway and another one targeting recurrent/metastatic cervical cancer patients expected to begin in 2024. Read the full article on Seeking Alpha
Analysis Article Nov 04

Will Precigen (NASDAQ:PGEN) Spend Its Cash Wisely?

We can readily understand why investors are attracted to unprofitable companies. For example, although...
Analysis Article Jul 18

Is Precigen (NASDAQ:PGEN) Using Debt In A Risky Way?

Warren Buffett famously said, 'Volatility is far from synonymous with risk.' It's only natural to consider a company's...
Analysis Article May 15

Things Look Grim For Precigen, Inc. (NASDAQ:PGEN) After Today's Downgrade

One thing we could say about the analysts on Precigen, Inc. ( NASDAQ:PGEN ) - they aren't optimistic, having just made...
Analysis Article Apr 18

Some Shareholders Feeling Restless Over Precigen, Inc.'s (NASDAQ:PGEN) P/S Ratio

With a median price-to-sales (or "P/S") ratio of close to 11.8x in the Biotechs industry in the United States, you...

Shareholder Returns

PGENUS BiotechsUS Market
7D-0.2%3.7%3.2%
1Y207.4%41.9%31.0%

Return vs Industry: PGEN exceeded the US Biotechs industry which returned 41.9% over the past year.

Return vs Market: PGEN exceeded the US Market which returned 31% over the past year.

Price Volatility

Is PGEN's price volatile compared to industry and market?
PGEN volatility
PGEN Average Weekly Movement12.8%
Biotechs Industry Average Movement10.6%
Market Average Movement7.1%
10% most volatile stocks in US Market16.1%
10% least volatile stocks in US Market3.2%

Stable Share Price: PGEN's share price has been volatile over the past 3 months compared to the US market.

Volatility Over Time: PGEN's weekly volatility (13%) has been stable over the past year, but is still higher than 75% of US stocks.

About the Company

FoundedEmployeesCEOWebsite
1998160Helen Sabzevariprecigen.com

Precigen, Inc.,a discovery and clinical-stage biopharmaceutical company, develops gene and cell therapies using precision technology to target diseases in areas of immuno-oncology, autoimmune disorders, and infectious diseases. The company offers therapeutic platforms consisting of AdenoVerse platform, which utilizes a library of proprietary adenovectors for gene delivery of therapeutic effectors, immunomodulators, and vaccine antigen; and UltraCAR-T to provide chimeric antigen receptor T cell therapies for cancer patients. It also develops programs based on the UltraCAR-T platform, including PRGN-3005 in Phase 1/1b clinical trial to treat advanced ovarian, fallopian tube, or primary peritoneal cancer; PRGN-3006 in Phase 1b trial for patients with relapsed or refractory acute myeloid leukemia and high-risk myelodysplastic syndromes; and PRGN-3007 in Phase 1/1b trial for the treatment of advanced receptor tyrosine kinase-like orphan receptor 1-positive, hematologic, and solid tumors.

Precigen, Inc. Fundamentals Summary

How do Precigen's earnings and revenue compare to its market cap?
PGEN fundamental statistics
Market capUS$1.56b
Earnings (TTM)-US$429.64m
Revenue (TTM)US$9.68m
151.7x
P/S Ratio
-3.4x
P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
PGEN income statement (TTM)
RevenueUS$9.68m
Cost of RevenueUS$46.16m
Gross Profit-US$36.47m
Other ExpensesUS$393.17m
Earnings-US$429.64m

Last Reported Earnings

Dec 31, 2025

Next Earnings Date

May 13, 2026

Earnings per share (EPS)-1.21
Gross Margin-376.62%
Net Profit Margin-4,436.62%
Debt/Equity Ratio445.6%

How did PGEN perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/05/07 23:17
End of Day Share Price 2026/05/07 00:00
Earnings2025/12/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Precigen, Inc. is covered by 10 analysts. 3 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Ying HuangBarclays
Derik de BruinBofA Global Research
Justin WalshB. Riley Securities, Inc.