Stoke Therapeutics, Inc.

NasdaqGS:STOK Stock Report

Market Cap: US$2.0b

Stoke Therapeutics Past Earnings Performance

Past criteria checks 0/6

Stoke Therapeutics has been growing earnings at an average annual rate of 5.5%, while the Biotechs industry saw earnings growing at 33.7% annually. Revenues have been growing at an average rate of 62.3% per year.

Key information

5.49%

Earnings growth rate

16.00%

EPS growth rate

Biotechs Industry Growth17.04%
Revenue growth rate62.25%
Return on equity-60.17%
Net Margin-753.60%
Last Earnings Update30 Jun 2026

Recent past performance updates

Recent updates

Seeking Alpha 5h

Stoke: 'Buy' On Zorevunersen NDA SCN1A DS And STK-002 Advancement

Summary Stoke Therapeutics remains a "Buy," driven by progress on zorevunersen for SCN1A Dravet Syndrome and robust clinical milestones ahead. The company expects an FDA meeting in H2 2026, rolling NDA submission in Q1 2027, and phase 3 EMPEROR data in Q3 2027 for zorevunersen. The advancement of STK-002 for autosomal dominant optic atrophy in the phase 1 OSPREY study showcases the TANGO platform's broader therapeutic potential. Strong cash position, with a runway into early 2028, supports continued R&D and milestone execution across lead and pipeline programs. Read the full article on Seeking Alpha
Narrative Update Jul 10

STOK: Phase 3 Dravet Data And NDA Timeline Will Drive Upside

Analysts have raised their fair value estimate for Stoke Therapeutics from $39.00 to $60.00, citing updated assumptions related to revenue growth, profitability, and a lower projected future P/E multiple. What’s in the News for Stoke Therapeutics Stoke Therapeutics has completed enrollment of 162 patients in the Phase 3 EMPEROR study of zorevunersen in Dravet syndrome.
Narrative Update Jun 26

None

Analysts have lifted their price target for Stoke Therapeutics from $34.25 to $45.10, citing updated assumptions around revenue growth, profitability, and a lower projected future P/E multiple as key drivers of the change. What’s in the News for Stoke Therapeutics No recent company specific news for Stoke Therapeutics was identified in the provided sources.
Analysis Article May 11

Stoke Therapeutics, Inc. (NASDAQ:STOK) Analysts Are Pretty Bullish On The Stock After Recent Results

As you might know, Stoke Therapeutics, Inc. ( NASDAQ:STOK ) just kicked off its latest quarterly results with some very...
New Narrative May 11

Phase III Trial And Payer Risks Will Shape Dravet Treatment Prospects

Catalysts About Stoke Therapeutics Stoke Therapeutics is a biotechnology company focused on RNA-based medicines, including zorevunersen for Dravet syndrome. What are the underlying business or industry changes driving this perspective?
Analysis Article Jan 12

Newsflash: Stoke Therapeutics, Inc. (NASDAQ:STOK) Analysts Have Been Trimming Their Revenue Forecasts

The analysts covering Stoke Therapeutics, Inc. ( NASDAQ:STOK ) delivered a dose of negativity to shareholders today, by...
Analysis Article Dec 05

Stoke Therapeutics, Inc.'s (NASDAQ:STOK) Shares Bounce 36% But Its Business Still Trails The Industry

Despite an already strong run, Stoke Therapeutics, Inc. ( NASDAQ:STOK ) shares have been powering on, with a gain of...
Analysis Article Oct 09

Stoke Therapeutics, Inc. (NASDAQ:STOK) Held Back By Insufficient Growth Even After Shares Climb 39%

Stoke Therapeutics, Inc. ( NASDAQ:STOK ) shares have continued their recent momentum with a 39% gain in the last month...
Analysis Article Aug 25

Improved Revenues Required Before Stoke Therapeutics, Inc. (NASDAQ:STOK) Stock's 49% Jump Looks Justified

Stoke Therapeutics, Inc. ( NASDAQ:STOK ) shares have continued their recent momentum with a 49% gain in the last month...
Analysis Article Aug 15

Stoke Therapeutics, Inc. (NASDAQ:STOK) Shares Could Be 25% Above Their Intrinsic Value Estimate

NasdaqGS:STOK 1 Year Share Price vs Fair Value Explore Stoke Therapeutics's Fair Values from the Community and select...
Analysis Article May 20

Stoke Therapeutics, Inc.'s (NASDAQ:STOK) Shares Bounce 28% But Its Business Still Trails The Industry

Stoke Therapeutics, Inc. ( NASDAQ:STOK ) shareholders would be excited to see that the share price has had a great...
Analysis Article Apr 16

Analysts Are More Bearish On Stoke Therapeutics, Inc. (NASDAQ:STOK) Than They Used To Be

Market forces rained on the parade of Stoke Therapeutics, Inc. ( NASDAQ:STOK ) shareholders today, when the analysts...
Analysis Article Apr 05

Stoke Therapeutics, Inc.'s (NASDAQ:STOK) 27% Dip Still Leaving Some Shareholders Feeling Restless Over Its P/SRatio

To the annoyance of some shareholders, Stoke Therapeutics, Inc. ( NASDAQ:STOK ) shares are down a considerable 27% in...
Analysis Article Feb 26

We're Hopeful That Stoke Therapeutics (NASDAQ:STOK) Will Use Its Cash Wisely

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although...
Seeking Alpha Feb 16

Stoke Therapeutics: A Pivotal Moment For This RNA Pioneer

Summary Stoke Therapeutics' RNA-based treatments for severe neurological and ophthalmic disorders, particularly zorevunersen for Dravet syndrome, show potential for long-term value beyond a single drug. Financials reveal high R&D spending and cash burn, but revenue growth from Acadia Pharmaceuticals collaboration suggests early monetization and potential non-dilutive funding. The Phase 3 EMPEROR study for zorevunersen is critical, with regulatory alignment and promising early data, but execution and long-term safety monitoring remain challenges. Stoke's broader pipeline, including treatments for SYNGAP1-related disorders, Rett syndrome, and Autosomal Dominant Optic Atrophy, could expand its market potential if RNA modulation proves broadly effective. Read the full article on Seeking Alpha
Analysis Article Nov 08

Earnings Update: Stoke Therapeutics, Inc. (NASDAQ:STOK) Just Reported And Analysts Are Trimming Their Forecasts

Stoke Therapeutics, Inc. ( NASDAQ:STOK ) just released its third-quarter report and things are looking bullish. Results...
Analysis Article Nov 06

Industry Analysts Just Made A Huge Upgrade To Their Stoke Therapeutics, Inc. (NASDAQ:STOK) Revenue Forecasts

Stoke Therapeutics, Inc. ( NASDAQ:STOK ) shareholders will have a reason to smile today, with the analysts making...

Revenue & Expenses Breakdown

How Stoke Therapeutics makes and spends money. Based on latest reported earnings, on an LTM basis.


Earnings and Revenue History

NasdaqGS:STOK Revenue, expenses and earnings (USD Millions)
DateRevenueEarningsG+A ExpensesR&D Expenses
30 Jun 2628-20882169
31 Mar 2632-17072145
31 Dec 25184-767138
30 Sep 252064159120
30 Jun 252005255104
31 Mar 25191505399
31 Dec 2437-894989
30 Sep 2417-1054787
30 Jun 2415-1044486
31 Mar 248-1094185
31 Dec 239-1054182
30 Sep 239-1034082
30 Jun 239-1054081
31 Mar 2315-994079
31 Dec 2212-1013978
30 Sep 229-1003873
30 Jun 226-963767
31 Mar 223-943463
31 Dec 210-863254
30 Sep 210-762947
30 Jun 210-672641
31 Mar 210-582335
31 Dec 200-522132
30 Sep 200-481930
30 Jun 200-431729
31 Mar 200-381427
31 Dec 190-321224
30 Sep 190-26920
30 Jun 190-21715
31 Mar 190-16611
31 Dec 180-1348

Quality Earnings: STOK is currently unprofitable.

Growing Profit Margin: STOK is currently unprofitable.


Free Cash Flow vs Earnings Analysis


Past Earnings Growth Analysis

Earnings Trend: STOK is unprofitable, but has reduced losses over the past 5 years at a rate of 5.5% per year.

Accelerating Growth: Unable to compare STOK's earnings growth over the past year to its 5-year average as it is currently unprofitable

Earnings vs Industry: STOK is unprofitable, making it difficult to compare its past year earnings growth to the Biotechs industry (64.1%).


Return on Equity

High ROE: STOK has a negative Return on Equity (-60.17%), as it is currently unprofitable.


Return on Assets


Return on Capital Employed


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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/08/05 21:40
End of Day Share Price 2026/08/05 00:00
Earnings2026/06/30
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

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Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Stoke Therapeutics, Inc. is covered by 22 analysts. 11 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Gregory HarrisonBofA Global Research
Thomas ShraderBTIG
Michelle GilsonCanaccord Genuity