Zevra Therapeutics, Inc.

NasdaqGS:ZVRA Stock Report

Market Cap: US$686.5m

Zevra Therapeutics Past Earnings Performance

Past criteria checks 3/6

Zevra Therapeutics has been growing earnings at an average annual rate of 35.2%, while the Pharmaceuticals industry saw earnings growing at 10.9% annually. Revenues have been growing at an average rate of 45.5% per year. Zevra Therapeutics's return on equity is 26.8%, and it has net margins of 42.1%.

Key information

35.21%

Earnings growth rate

44.45%

EPS growth rate

Pharmaceuticals Industry Growth5.95%
Revenue growth rate45.49%
Return on equity26.77%
Net Margin42.07%
Last Earnings Update30 Jun 2026

Recent past performance updates

Recent updates

Narrative Update Jul 24

CHMP/EMA Refusal & Financial Risk Analysis

Zevra Therapeutics received a negative opinion (refusal) from the European Medicines Agency’s (EMA) Committee for Medicinal Products for Human Use (CHMP) regarding the Marketing Authorization Application (MAA) for Meplyffa (arimoclomol) for the treatment of Niemann-Pick disease type C (NPC). Following the announcement, the stock reacted with an immediate ~30% decline, dropping to the $8.56 level.
Seeking Alpha Jul 23

Zevra Therapeutics: Worthy Of An Initial Holding

Summary Zevra Therapeutics surged after Miplyffa’s patent was listed in the FDA Orange Book, granting exclusivity through 2041. ZVRA achieved FY25 net sales of $87.4M, moved into profitability, retired all debt, and now holds $236.8M in cash and investments. The pipeline is focused on late-stage celiprolol for VEDS, with no clinical competition and FDA Orphan and Breakthrough Therapy designations. Trading at ~9x FY27E EPS (net of cash), ZVRA offers expansion potential, a clean balance sheet, and possible takeout appeal—supporting a small purchase. Read the full article on Seeking Alpha
New Narrative Jul 20

Zevra Therapeutics: Galloping Through a Green Safari

From Prodrugs to a Rare Disease Powerhouse Zevra Therapeutics wasn’t always a rare disease contender. Originally known as KemPharm , the company spent years focused on prodrug technology for ADHD and pain management.
Narrative Update Jul 02

ZVRA: Extended Patent Exclusivity May Support Longer NPC Revenue Runway

The analyst price target for Zevra Therapeutics has shifted from $18 to $21, with analysts pointing to extended Miplyffa patent exclusivity and updated cash flow assumptions as key drivers of their higher valuation work. Analyst Commentary on Zevra Therapeutics Recent Street research on Zevra Therapeutics has focused on how extended Miplyffa intellectual property coverage could affect long term cash flow modeling, with several firms updating their price targets and assumptions around the duration of exclusivity.
Narrative Update Jun 18

ZVRA: Extended Rare Disease IP Runway Will Drive Future Upside Potential

Analysts have raised the fair value estimate for Zevra Therapeutics to $35 from $26, aligning it with updated Street price targets in the $27 to $35 range, as they incorporate extended Miplyffa intellectual property protection and a higher future P/E assumption into their models. Analyst Commentary Recent research updates on Zevra Therapeutics cluster around one theme: bullish analysts are reassessing the stock’s upside as they factor in longer intellectual property protection for Miplyffa and refine their cash flow models.
New Narrative Jun 09

Discounted Exit Multiple Approach (DEM)

Disclaimer: This financial analysis is for informational purposes only and does not constitute investment advice. Zevra Therapeutics is a rare disease pharmaceutical company fundamentally driven by a single commercial product.
Narrative Update Jun 03

ZVRA: NPC Diagnosis Expansion Will Drive Future Upside Potential

Analysts have raised their average price target for Zevra Therapeutics to $23 from $22, citing early Miplyffa adoption trends, positive views on potential expansion opportunities, and ongoing adjustments to growth, margin and P/E assumptions in their models. Analyst Commentary Bullish analysts are leaning into a constructive view on Zevra Therapeutics, framing the updated US$23 average price target as grounded in observable Miplyffa adoption trends and modeled upside from expansion opportunities.
Narrative Update Apr 23

ZVRA: NPC Diagnosis Expansion And EU Decision Will Drive Future Upside Potential

Narrative Update: Zevra Therapeutics The updated analyst price target for Zevra Therapeutics is now $23, a $1 increase, as analysts point to the launch progress of Miplyffa, expectations for continued U.S. market penetration, and potential future catalysts including EU approval, patent term extension, and celiprolol development in VEDS. Analyst Commentary Bullish analysts are highlighting Zevra Therapeutics as a name where current valuation is closely linked to the rollout of Miplyffa and a set of identifiable potential catalysts.
Narrative Update Apr 08

ZVRA: NPC Diagnosis Expansion Will Drive Future Upside Potential

Analysts have maintained Zevra Therapeutics' fair value estimate at $26.00, with slight tweaks to growth, margin, and future P/E assumptions. Recent Street research highlights a $23 price target, supported by views that current pricing reflects conservative Miplyffa adoption and potential upside from broader patient reach and future regulatory or pipeline milestones.
Narrative Update Mar 24

ZVRA: Expanding NPC Diagnosis And EU Decision Will Drive Future Upside

Analysts have kept Zevra Therapeutics' fair value estimate steady at $26.00 while updating their assumptions on Miplyffa's launch trajectory and potential upside from EU approval, expanded U.S. adoption, and celiprolol optionality, which they note is reflected in Street price targets moving toward $23.00. Analyst Commentary Bullish analysts are framing Zevra's current share price as tied closely to conservative expectations for Miplyffa, largely anchored to the already diagnosed U.S. Niemann Pick type C population.
Narrative Update Mar 10

ZVRA: Growing NPC Access And Data Will Support Long-Term Rare Disease Upside

Analysts have maintained their $26.00 price target for Zevra Therapeutics, citing updated assumptions that reflect slightly different estimates for revenue growth, profit margins, and future P/E, without materially changing their overall view of the stock's valuation. What's in the News Zevra Therapeutics appointed Justin Renz as Chief Financial Officer, effective March 9, 2026.
Narrative Update Feb 24

ZVRA: Expanded Access And NPC Data Will Support Long-Term Rare Disease Upside

Analysts have kept their Zevra Therapeutics price target steady at $26.00. This points to largely unchanged fair value assumptions, even as they refine inputs such as revenue growth, profit margins and future P/E expectations.
Narrative Update Feb 09

ZVRA: Expanded Access And NPC Data Will Support Long-Term Rare Disease Upside

Analysts have maintained their price target on Zevra Therapeutics at $26.00, citing only modest tweaks to assumptions around revenue growth, profit margins, the discount rate, and future P/E that did not materially change their overall view. What's in the News Zevra presented four posters at the 22nd Annual WORLDSymposium highlighting new data on MIPLYFFA (arimoclomol) for Niemann Pick Disease Type C.
Narrative Update Jan 26

ZVRA: Expanded Access Deal Will Support Long-Term Rare Disease Upside

Narrative Update: Zevra Therapeutics Analyst Price Target The analyst price target for Zevra Therapeutics is now set at US$26.00. Analysts cite small adjustments to revenue growth assumptions, profit margin expectations, and future P/E estimates as key drivers for the updated view.
Narrative Update Jan 11

ZVRA: Expanded Rare Disease Access Agreement Will Support Long-Term Upside

Analysts have maintained their price target for Zevra Therapeutics at US$26.00, citing only modest adjustments to assumptions around revenue growth, profit margins and future P/E. Taken together, these changes do not alter their overall view of the company’s valuation.
Narrative Update Dec 26

ZVRA: Future Rare Disease Portfolio Will Support Long-Term Upside

Analysts have modestly increased their price target on Zevra Therapeutics to $26.00 per share, citing slightly stronger long term revenue growth and profit margin assumptions, alongside a marginally lower projected future price to earnings multiple. What's in the News Chief Financial Officer and Treasurer R.
Narrative Update Dec 12

ZVRA: Future Rare Disease Approvals Will Drive Long-Term Upside

Analysts have reduced their price target on Zevra Therapeutics by 3.00 dollars to 26.00 dollars, citing expectations for slower revenue growth, slightly lower profit margins, and a modestly higher discount rate, partially offset by a lower anticipated future price to earnings multiple. What's in the News Chief Financial Officer and Treasurer R.
Analysis Article Nov 08

Zevra Therapeutics, Inc. (NASDAQ:ZVRA) Just Reported And Analysts Have Been Cutting Their Estimates

It's been a mediocre week for Zevra Therapeutics, Inc. ( NASDAQ:ZVRA ) shareholders, with the stock dropping 13% to...
Analysis Article Nov 03

Zevra Therapeutics (NASDAQ:ZVRA) Is Using Debt Safely

Howard Marks put it nicely when he said that, rather than worrying about share price volatility, 'The possibility of...
Analysis Article Sep 08

What You Can Learn From Zevra Therapeutics, Inc.'s (NASDAQ:ZVRA) P/S After Its 26% Share Price Crash

Zevra Therapeutics, Inc. ( NASDAQ:ZVRA ) shares have had a horrible month, losing 26% after a relatively good period...
Analysis Article Jul 10

Zevra Therapeutics, Inc.'s (NASDAQ:ZVRA) 26% Jump Shows Its Popularity With Investors

Zevra Therapeutics, Inc. ( NASDAQ:ZVRA ) shares have continued their recent momentum with a 26% gain in the last month...
Analysis Article May 22

Revenues Tell The Story For Zevra Therapeutics, Inc. (NASDAQ:ZVRA) As Its Stock Soars 26%

Zevra Therapeutics, Inc. ( NASDAQ:ZVRA ) shareholders would be excited to see that the share price has had a great...
User avatar
New Narrative Apr 29

MIPLYFFA Launch Will Spark European Expansion In 2025

Successful MIPLYFFA launch and European expansion plans indicate potential revenue growth and stable streams through strong demand and patient engagement.
Analysis Article Mar 10

Investors Appear Satisfied With Zevra Therapeutics, Inc.'s (NASDAQ:ZVRA) Prospects

When close to half the companies in the Pharmaceuticals industry in the United States have price-to-sales ratios (or...
Analysis Article Nov 15

Here's What Analysts Are Forecasting For Zevra Therapeutics, Inc. (NASDAQ:ZVRA) After Its Third-Quarter Results

As you might know, Zevra Therapeutics, Inc. ( NASDAQ:ZVRA ) last week released its latest third-quarter, and things did...
Analysis Article Aug 30

Investors Appear Satisfied With Zevra Therapeutics, Inc.'s (NASDAQ:ZVRA) Prospects As Shares Rocket 34%

Zevra Therapeutics, Inc. ( NASDAQ:ZVRA ) shares have continued their recent momentum with a 34% gain in the last month...

Revenue & Expenses Breakdown

How Zevra Therapeutics makes and spends money. Based on latest reported earnings, on an LTM basis.


Earnings and Revenue History

NasdaqGS:ZVRA Revenue, expenses and earnings (USD Millions)
DateRevenueEarningsG+A ExpensesR&D Expenses
30 Jun 26136577515
31 Mar 261221177914
31 Dec 25106787813
30 Sep 2584297318
30 Jun 2562-47326
31 Mar 2541-926533
31 Dec 2424-1065542
30 Sep 2424-905444
30 Jun 2424-674446
31 Mar 2428-493843
31 Dec 2327-463539
30 Sep 2317-202534
30 Jun 2317-172327
31 Mar 239-382025
31 Dec 2210-271619
30 Sep 2211-351316
30 Jun 2210-301112
31 Mar 2220-171010
31 Dec 2129-63910
30 Sep 2128-65910
30 Jun 2128-6699
31 Mar 2123-5588
31 Dec 2013-1388
30 Sep 2012-1478
30 Jun 2022-81010
31 Mar 2015-181112
31 Dec 1913-251119
30 Sep 1911-241323
30 Jun 190-421232
31 Mar 190-431338
31 Dec 180-561341
30 Sep 180-621341
30 Jun 180-571333
31 Mar 180-531328
31 Dec 170-431320
30 Sep 170-431323
30 Jun 170-451321
31 Mar 170-301421
31 Dec 160-171420
30 Sep 160-161417
30 Jun 160-131317
31 Mar 160-521215
31 Dec 150-55914

Quality Earnings: ZVRA has a large one-off gain of $33.1M impacting its last 12 months of financial results to 30th June, 2026.

Growing Profit Margin: ZVRA became profitable in the past.


Free Cash Flow vs Earnings Analysis


Past Earnings Growth Analysis

Earnings Trend: ZVRA has become profitable over the past 5 years, growing earnings by 35.2% per year.

Accelerating Growth: ZVRA has become profitable in the last year, making the earnings growth rate difficult to compare to its 5-year average.

Earnings vs Industry: ZVRA has become profitable in the last year, making it difficult to compare its past year earnings growth to the Pharmaceuticals industry (0.2%).


Return on Equity

High ROE: ZVRA's Return on Equity (26.8%) is considered high.


Return on Assets


Return on Capital Employed


Discover strong past performing companies

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/08/09 01:56
End of Day Share Price 2026/08/07 00:00
Earnings2026/06/30
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Zevra Therapeutics, Inc. is covered by 17 analysts. 9 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Kenneth TrbovichBrean Capital Historical (Janney Montgomery)
Kambiz YazdiBTIG
Sumant Satchidanand KulkarniCanaccord Genuity