COMPASS Pathways plc

NasdaqGS:CMPS Stock Report

Market Cap: US$1.8b

COMPASS Pathways Past Earnings Performance

Past criteria checks 0/6

COMPASS Pathways's earnings have been declining at an average annual rate of -31%, while the Biotechs industry saw earnings growing at 34.1% annually.

Key information

-31.02%

Earnings growth rate

-7.16%

EPS growth rate

Biotechs Industry Growth17.04%
Revenue growth raten/a
Return on equity-466.31%
Net Marginn/a
Last Earnings Update30 Jun 2026

Recent past performance updates

Recent updates

Narrative Update Aug 06

CMPS: Phase 3 Durability And FDA Openness Balance Competitive And Execution Risks

Analysts now set the primary fair value estimate for COMPASS Pathways at $13, down from $17. This change reflects updated views on COMP360's commercial headroom compared with existing therapies, a somewhat higher discount rate, and tempered expectations for future P/E multiples, despite supportive Phase 3 data and a generally constructive regulatory backdrop for psychedelics.
Seeking Alpha Jul 28

Compass Pathways: The Psilocybin Biotech Leader With Strong Momentum

Summary CMPS leads regulated psilocybin with two successful Phase 3 trials and a rolling FDA submission, giving COMP360 a valuable head start in treatment-resistant depression. The core case rests on vast unmet need in depression, while encouraging PTSD data and other possible uses provide meaningful long-term upside beyond the first indication. Lilly’s move for Atai validates the field and raises the competitive bar, but CMPS retains its clinical lead and cash runway; a 2% pro-forma position keeps risk proportionate. Read the full article on Seeking Alpha
Narrative Update Jul 23

CMPS: Phase 3 Durability And Favorable FDA Stance Will Drive Upside

Analysts have raised the fair value estimate for Compass Pathways stock to $17.00 from $8.00, citing stronger confidence in COMP360's durable efficacy profile, supportive recent Phase 3 data, and a regulatory backdrop that they view as increasingly receptive to psychedelic treatments. Analyst Commentary Recent Street research on Compass Pathways highlights a mix of enthusiasm around COMP360's Phase 3 data and a more cautious undercurrent that focuses on execution, valuation, and regulatory timing.
Narrative Update Jul 08

CMPS: Phase 3 Durability Data Will Underpin Potential 2027 Launch Upside

The analyst price target for Compass Pathways has been raised to $24.47 from $21.92. Analysts point to supportive 26-week COMP360 durability data, a consistent safety profile, and a clearer path toward a potential 2027 approval and commercial launch as key reasons for the updated view.
New Narrative Apr 02

Phase III Progress And PTSD Expansion Will Reshape Long Term Psychedelic Mental Health Treatment

Catalysts About COMPASS Pathways COMPASS Pathways is a mental health company developing COMP360 psilocybin treatment for conditions such as treatment resistant depression and PTSD. What are the underlying business or industry changes driving this perspective?
New Narrative Mar 19

Phase III Completion And PTSD Expansion Will Support A Durable Mental Health Franchise

Catalysts About COMPASS Pathways COMPASS Pathways is a mental health company developing COMP360 psilocybin treatment for conditions such as treatment resistant depression and PTSD. What are the underlying business or industry changes driving this perspective?
New Narrative Mar 04

Phase III Trial Dependence Will Dominate Near Term While Long Term Potential Remains

Catalysts About COMPASS Pathways COMPASS Pathways is a mental health company developing COMP360, a psilocybin-based treatment for conditions such as treatment resistant depression and PTSD. What are the underlying business or industry changes driving this perspective?
Analysis Article Dec 08

Is COMPASS Pathways (NASDAQ:CMPS) Weighed On By Its Debt Load?

Some say volatility, rather than debt, is the best way to think about risk as an investor, but Warren Buffett famously...
Analysis Article Aug 07

Is COMPASS Pathways (NASDAQ:CMPS) Using Debt Sensibly?

NasdaqGS:CMPS 1 Year Share Price vs Fair Value Explore COMPASS Pathways's Fair Values from the Community and select...
Seeking Alpha Feb 28

Compass Pathways: Betting On The Future Of Psilocybin Therapy

Summary Compass Pathways is positioned to leverage regulatory tailwinds and compelling clinical data, despite broader skepticism and high cash burn in the psychedelic biotech sector. The company has a financial cushion with cash reserves of $165.1 million, providing 4-6 quarters of runway before needing additional capital. COMP360 shows promise in treating treatment-resistant depression and PTSD, with significant clinical trial results and potential long-term economic benefits. Regulatory hurdles and scientific doubts remain, but if Compass achieves FDA approval, its current market valuation could be deeply discounted relative to its long-term potential. Read the full article on Seeking Alpha
Analysis Article Jan 04

Does COMPASS Pathways (NASDAQ:CMPS) Have A Healthy Balance Sheet?

Some say volatility, rather than debt, is the best way to think about risk as an investor, but Warren Buffett famously...
Seeking Alpha Nov 01

Compass Pathways: Minor Delay Of COMP360 Data Brings About Buy Opportunity

Summary Compass Pathways plc obtained positive results from phase 2b study using COMP360 for treatment resistant depression patients; Primary endpoint met with statistically significant p-value of p<0.001. Top-line results from the phase 3 COMP005 study, using COMP360 for treatment-resistant depression patients, expected in Q2 of 2025. The global treatment-resistant depression treatment market size is projected to grow to $4 billion by 2033. Other indications being explored using COMP360 as a synthetic psilocybin are anorexia nervosa and post-traumatic stress disorder. Read the full article on Seeking Alpha
Seeking Alpha Aug 19

Compass Pathways: Sector-Wide Reality Check Needed Post FDA Lykos MDMA Decision

Summary The psychedelics sector has suffered a big blow, with the US FDA knocking back a New Drug Application for MDMA-assisted therapy. The potential for a negative FDA decision had been well-flagged by an advisory committee report in June, so the market may have already priced in the downside. Arguments that the negative FDA decision on MDMA may actually be good news for Compass Pathways plc and peers are not persuasive. The FDA decision is not the end of the road for the psychedelics sector, but Compass Pathways and peers face serious challenges regarding regulatory approval, access to capital and commercialization. The group took action to strengthen its balance sheet in 2023, but my cash burn analysis indicates that further capital injections will be needed before the end of 2025. Read the full article on Seeking Alpha
Seeking Alpha Jul 08

Compass Pathways: Buy It For Its Promising Psychedelic Mental Health Therapies

Summary COMPASS Pathways' lead drug, COMP360, is a synthetic psilocybin in Phase 3 trials for TRD and Phase 2 for PTSD and AN. The company addresses unmet mental health needs through psychedelic therapies. COMP360 showed promising results in Phase 2 trials for PTSD, with significant improvements in depression symptoms. Industry-wide regulatory uncertainties persist, highlighted by the FDA's recent decision against MDMA for PTSD. I believe CMPS is undervalued. Its substantial aggregate TAM and strategic collaborations bode well for potential FDA approval and commercialization. Read the full article on Seeking Alpha
Seeking Alpha May 23

Psychedelics Closer To Commercialization; Compass Far And Away The Leader

Summary Regulatory risk in the psychedelic industry is decreasing, which is a positive sign for investors. Institutional investors are becoming more willing to invest in leading psychedelic companies through private placements. Analyst Alex Carchidi discusses Compass, Cybin, Atai, and MindMed seeing improvements in their balance sheets and clinical trial data. Read the full article on Seeking Alpha
Seeking Alpha Apr 25

COMPASS Pathways: Will MDMA-Assisted Therapy Pave The Way Or Slam The Door Shut?

Summary The US FDA is due to make a decision regarding MDMA-assisted therapy in August 2024 – this will be a critical event for the future of COMPASS Pathways. COMPASS Pathways’ share price has exhibited extreme volatility over the last year, highlighting the speculative nature of investing in the psychedelics sector. COMPASS Pathways has experienced delays with its COMP 005 clinical trial, but is confident that its COMP360 New Drug Application timeline remains unchanged. The departure of the company’s co-founders came as a surprise, and follows on from the sudden exit of the group’s CFO in late 2023. Read the full article on Seeking Alpha
Seeking Alpha Feb 08

Compass Pathways: Psilocybin Developer A Potentially Intriguing, Contrarian Play

Summary Compass Pathways plc, a biotech company based in London, is developing a psilocybin-based therapy for CNS disorders. The company's shares declined by over 80% in 2022 due to safety concerns and regulatory hurdles. Psilocybin is classified as a Schedule I substance in the U.S., posing challenges for commercial marketing in the country. Compass' COMP-360 therapy involves sessions with therapists and digital support, and has met efficacy endpoints in a Phase 2 study. There are multiple reasons to doubt the therapy can be approved, and Compass has a high cash burn, but Phase 3 data due this year may support an approval push, if positive. An interesting contrarian play, for those with a higher appetite for risk. Read the full article on Seeking Alpha
Analysis Article Dec 06

Companies Like COMPASS Pathways (NASDAQ:CMPS) Are In A Position To Invest In Growth

Just because a business does not make any money, does not mean that the stock will go down. For example, although...
Seeking Alpha Oct 19

Booker again pushes for easier access to psychedelics for terminally ill patients

Sen. Cory Booker (D-N.J.) is again pushing for easier access to psychedelic drugs, including psilocybin, the active psychedelic compound in "magic mushrooms," and MDMA, for terminally ill patients. In July, Booker and Sen. Rand Paul (R-Ky.) introduced legislation to clarify that the Right to Try Act allows for access to some psychedelics and cannabis. Companion legislation was also filed in the House. In a video posted to Twitter, Booker said that psilocybin and MDMA particularly "are showing incredible results for helping people with PTSD, with trauma, even with anxiety and depression." Several companies are examining psychedelics for mental health disorders, including COMPASS Pathways (NASDAQ:CMPS), Cybin (NYSE:CYBN), atai Life Sciences (NASDAQ:ATAI), and MindMed (NASDAQ:MNMD). Check out why Seeking Alpha contributor Stephen Tobin is bullish on atai Life Sciences (ATAI).

Revenue & Expenses Breakdown

How COMPASS Pathways makes and spends money. Based on latest reported earnings, on an LTM basis.


Earnings and Revenue History

NasdaqGS:CMPS Revenue, expenses and earnings (USD Millions)
DateRevenueEarningsG+A ExpensesR&D Expenses
30 Jun 260-39469117
31 Mar 260-19258116
31 Dec 250-28861115
30 Sep 250-2376194
30 Jun 250-1386399
31 Mar 250-1386499
31 Dec 240-1555998
30 Sep 240-14454100
30 Jun 240-1395290
31 Mar 240-1295082
31 Dec 230-1184975
30 Sep 230-1175166
30 Jun 230-1025058
31 Mar 230-954853
31 Dec 220-924551
30 Sep 220-864846
30 Jun 220-844645
31 Mar 220-804341
31 Dec 210-723934
30 Sep 210-653127
30 Jun 210-662823
31 Mar 210-643120
31 Dec 200-602819
30 Sep 200-492419
30 Jun 200-382016
31 Mar 200-251113
31 Dec 190-20910

Quality Earnings: CMPS is currently unprofitable.

Growing Profit Margin: CMPS is currently unprofitable.


Free Cash Flow vs Earnings Analysis


Past Earnings Growth Analysis

Earnings Trend: CMPS is unprofitable, and losses have increased over the past 5 years at a rate of 31% per year.

Accelerating Growth: Unable to compare CMPS's earnings growth over the past year to its 5-year average as it is currently unprofitable

Earnings vs Industry: CMPS is unprofitable, making it difficult to compare its past year earnings growth to the Biotechs industry (67.9%).


Return on Equity

High ROE: CMPS has a negative Return on Equity (-466.31%), as it is currently unprofitable.


Return on Assets


Return on Capital Employed


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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/08/09 20:16
End of Day Share Price 2026/08/07 00:00
Earnings2026/06/30
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

COMPASS Pathways plc is covered by 22 analysts. 14 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Madison Wynne El-SaadiB. Riley Securities, Inc.
Thomas ShraderBTIG
Sumant Satchidanand KulkarniCanaccord Genuity